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Hepatitis-associated aplastic anaemia: surveillance of frequency,clinico-haematological features, and demographic distribution at a tertiary care hospital in Pakistan.
J Pak Med Assoc
January 2023
Department of Pathology, Laboratory Medicine and Oncology, Aga Khan University, Karachi, Pakistan.
Objective: We aim to document the frequency of HAAA cases among AA patients presenting at a tertiary care hospital, and to determine the most common agents (viral/drug induced) and Clinico-haematological features among HAAA patients at a tertiary care hospital.
Methods: This study was a retrospective review, conducted at a tertiary care hospital in Karachi, Pakistan.
Results: A total of 21 patients were included in the study.
Aplastic anemia following viral hepatitis.
JAAPA
October 2013
Alexandra Klinchenko is a recent graduate of the PA program at Marietta College in Marietta, Ohio. William A. Childers, Jr., is academic coordinator for the Marietta College PA program and practices primary care at the Veterans Affairs hospital in Clarksburg, West Virginia. The authors have indicated no relationships to disclose related to the content of this article.
Post-hepatitis aplastic anemia is a rare but severe variant of aplastic anemia. Early diagnosis and treatment via stem cell transplant can improve patient survival.
View Article and Find Full Text PDF[Outcome of allogeneic hematopoietic stem cell transplantation from HLA-matched sibling donor for 41 cases of severe aplastic anemia].
Zhonghua Xue Ye Xue Za Zhi
August 2012
Institute of Hematology and Blood Diseases Hospital, Tianjin, China.
Objective: To evaluate the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) from HLA-matched sibling donor (MSD allo-HSCT) for severe aplastic anemia (SAA).
Methods: The clinical data of 41 SAA patients received MSD allo-HSCT from May. 2003 to Aug.
Systemic complications of trinitrotoluene (TNT) in exposed workers.
Cutan Ocul Toxicol
March 2013
Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Islamic Republic of Iran.
Introduction: 2,4,6-trinitrotoluene (TNT) has been widely used as an explosive. TNT can induce some well-recognized toxic impacts comprising toxic hepatitis, aplastic anemia and cataract. The aim of study was evaluation of TNT exposed workers for systemic complication.
View Article and Find Full Text PDFConcise review: Anemia caused by viruses.
Stem Cells
November 2011
Centre des Innovations Thérapeutiques en Oncologie et Hématologie, CHU Saint-Louis, Paris, France.
Most of the viruses known to be associated with anemia in human tend to persistently infect their host and are noncytopathic or poorly cytopathic for blood cell progenitors. Infections with Epstein-Barr virus, cytomegalovirus, varicella-zoster virus, human herpes virus 6 (HHV-6), B19 parvovirus, human immunodeficiency virus, hepatitis A and C viruses and the putative viral agent associated with non-A-G post-hepatitis aplastic anemia have been reported in association with anemia. Nevertheless, a direct cytotoxic effect on erythroid progenitors has been clearly demonstrated only for human parvovirus B19 and evocated for HHV-6.
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