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Twenty-four-hour Normothermic Ex Vivo Heart Perfusion With Low Flow Functional Assessment in an Adult Porcine Model.
Transplantation
June 2024
Department of Surgery and ECLS Laboratory, University of Michigan Medical School, Ann Arbor, MI.
Background: Cold static storage and normothermic ex vivo heart perfusion are routinely limited to 6 h. This report describes intermittent left atrial (LA) perfusion that allows cardiac functional assessment in a working heart mode.
Methods: Using our adult porcine model, general anesthesia was induced and a complete cardiectomy was performed following cardioplegic arrest.
Twenty-four-hour rhythmicities in disorders of consciousness are associated with a favourable outcome.
Commun Biol
November 2023
CAP Team (Cognition Auditive et Psychoacoustique), Lyon Neuroscience Research Centre (Université Claude Bernard Lyon 1, INSERM U1028, CNRS UMR5292), 95 boulevard Pinel, Bron, France.
Fluctuations of consciousness and their rhythmicities have been rarely studied in patients with a disorder of consciousness after acute brain injuries. 24-h assessment of brain (EEG), behaviour (eye-opening), and circadian (clock-controlled hormones secretion from urine) functions was performed in acute brain-injured patients. The distribution, long-term predictability, and rhythmicity (circadian/ultradian) of various EEG features were compared with the initial clinical status, the functional outcome, and the circadian rhythmicities of behaviour and clock-controlled hormones.
View Article and Find Full Text PDFTwenty-Four Hour Normothermic Ex Vivo Heart Perfusion With Hemofiltration In an Adult Porcine Model.
Transplant Proc
November 2023
Department of Surgery and ECLS Laboratory, University of Michigan Medical School, Ann Arbor, MI; Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI. Electronic address:
Background: Historically, cardiac transplantation relied on cold static storage at 5 °C for ex vivo myocardial preservation. Currently, machine perfusion is the standard of care at many transplant centers. These storage methods are limited to 12 hours.
View Article and Find Full Text PDFST-Segment Elevation: An Unexpected Culprit.
J Cardiovasc Dev Dis
September 2023
Cardiology Department, Centro Hospitalar Universitário de Santo António, Largo do Prof. Abel Salazar, 4099-001 Porto, Portugal.
The clinical presentation of pulmonary embolism (PE) and acute coronary syndrome can be similar. We report a case of a patient presenting with antero-septal ST-segment elevation after cardiac arrest, found to have acute-PE-mimicking ST-segment elevation myocardial infarction (STEMI), treated with aspiration thrombectomy and catheter-directed thrombolysis (CDT). A 78-year-old man was admitted with dyspnea, chest pain and tachycardia.
View Article and Find Full Text PDFTwenty-four hour ambulatory blood pressure monitoring in patients with stable heart failure. Prevalence and associated factors.
Rev Esp Cardiol (Engl Ed)
November 2023
Servicio de Cardiología, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
Introduction And Objectives: Hypertension is highly common in heart failure (HF). However, there is limited information on its prevalence, circadian variation, and relationship with the various HF phenotypes. The objective of this study was to describe the prevalence of hypertension and its patterns in HF.
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