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Alzheimers Dement
December 2024
Frontotemporal Disorders Unit and Massachusetts Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Background: Neurodegeneration in sporadic early-onset Alzheimer disease (EOAD) is topographically heterogeneous, as suggested by variability in syndromic presentation. We performed an unsupervised clustering analysis of structural MRI data to identify anatomical subtypes of EOAD. We hypothesized that distinct clusters will be present but will: (1) share areas of overlap focused around posterior regions of our newly developed EOAD signature of cortical atrophy (Touroutoglou et al.
View Article and Find Full Text PDFTopographic Anatomy and Step-Wised Harvest of Intermuscular Occipital Artery in Far Lateral Approach.
World Neurosurg
January 2025
Xuanwu Hospital, Capital Medical University, Beijing, China; Samii Clinial Neuroanatomy Research and Education Center of Xuanwu Hospital, Beijing, China. Electronic address:
Background: The occipital artery (OA) is an important donor artery for intracranial and extracranial bypass surgery, but its path is tortuous, making it difficult to harvest. Part of the traditional intermuscular OA is not covered by muscle and is easily damaged during surgery. Currently, there are few reports on how to protect this segment of the OA.
View Article and Find Full Text PDFThe Influence of Craniometric Variation on the Position of Mandibular Foramen: A Cadaveric Cross-Sectional Study.
Medicina (Kaunas)
November 2024
Department of Operative Surgery and Topographic Anatomy, First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.
: the mandibular foramen is an essential anatomic landmark in performing various dental and surgical procedures, including inferior alveolar nerve block (IANB). However, its position may vary based on the individual morpho-functional features of the skull and face. This study aims to conduct a personalized assessment of the location of the mandibular foramen in various shapes of skulls, faces, and mandibles.
View Article and Find Full Text PDFBackground: Understanding peripheral ulnar nerve anatomy is necessary to refine surgical treatment of ulnar nerve injuries. This study topographically mapped the ulnar nerve and its distal branch points from a well-defined surgical landmark and assessed for variations in interfascicular motor arrangement and branch size.
Methods: Fifty-four cadaveric upper extremities were dissected to expose the distal ulnar nerve and its branches (dorsal cutaneous (DCB), volar sensory (VSB), and motor branches).
Recent years have seen the development of various classifications of muscle injuries, primarily based on the topographic location within the bone-tendon-muscle chain. This paper proposes an enhanced nomenclature for muscle injuries that incorporates histoarchitectural definitions alongside topographic classifications, emphasizing the importance of connective tissue damage characterization. A detailed understanding of the distinct anatomical and histological characteristics of tendon, aponeurosis, and fascia is essential for consistent terminology.
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