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Cardioesophageal Reflex. Should it trigger clinician's response?
Am J Med
January 2025
Professor of Medicine, Department of Cardiology, Tufts Medical Center, (Tufts University School of Medicine), Boston, MA 02111, USA. Electronic address:
Cardiologists and gastroenterologists often encounter the coexistence of symptoms and functional abnormalities, but determining causation is more difficult. In 1962 Smith and Papp first coined the term "linked angina". Their statement was preceded by the experiment whereby increase in bile duct pressure elicited the typical chest pain in patients with ischemic heart disease.
View Article and Find Full Text PDFPrevalence and risk factors of gastroesophageal reflux disease among adults attending primary healthcare in Bahrain.
J Family Med Prim Care
December 2024
Associate Professor, Department of Family and Community Medicine, Arabian Gulf University, Kingdom of Bahrain.
Background: Gastroesophageal reflux disease (GERD) is one of the most diagnosed digestive disorders, with much-conducted research assessing its prevalence and risk factors associated with it worldwide. However, there are no published previous studies to determine such disease and its burden in Bahrain. Hence, this study aims to estimate the prevalence and evaluate the risk factors associated with GERD among adults attending primary care in Bahrain.
View Article and Find Full Text PDFEffects of atmospheric pressure change during flight on insulin pump delivery and glycaemic control of pilots with insulin-treated diabetes: an in vitro simulation and a retrospective observational real-world study.
Diabetologia
January 2025
Faculty of Health and Medical Science, University of Surrey, Guildford, UK.
Article Synopsis
- - The study explores how atmospheric pressure changes during flights can influence insulin delivery from pumps in people with type 1 diabetes, potentially leading to issues like hypoglycaemia.
- - An in vitro flight simulation mimicking airline conditions revealed that insulin pumps can over-deliver and under-deliver insulin at different stages of flight, particularly significant during emergency decompression scenarios.
- - Real-world data from pilots using continuous subcutaneous insulin infusion (CSII) showed that insulin levels remained stable with only a small percentage of blood glucose readings falling outside the safe range, indicating effective management while flying.
Deprescribing strategies for proton pump inhibitors.
JAAPA
November 2024
Julia Young, Jordan A. Fuller, and Corey M. Guidry are assistant professors at the University of Oklahoma College of Pharmacy in Oklahoma City, Okla. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Article Synopsis
- Proton pump inhibitors (PPIs) are commonly used medications for treating gastric-acid related diseases due to their effectiveness and better tolerability compared to other treatments.
- Long-term use of PPIs can lead to various adverse reactions, highlighting the need for careful management of their use.
- The article outlines guidelines for both short- and long-term PPI use and provides strategies for clinicians to safely reduce unnecessary prescriptions.
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