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A novel genomic island encodes vibrioferrin synthesis in the marine pathogen Photobacterium damselae subsp. damselae.
Microb Pathog
February 2025
Department of Microbiology and Parasitology, Aquatic One Health Research Center (ARCUS), Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain. Electronic address:
Article Synopsis
- The study discovered a new genomic island (pddGI-1) in the marine pathogen Photobacterium damselae, located on chromosome II.
- This genomic island shares features with other islands in Vibrio species and consists of genes for antioxidant defense, energy metabolism, and systems that modify DNA.
- The pddGI-1 also includes a complete system for vibroferrin, which helps the bacteria thrive in low-iron environments, suggesting that strains with this island have a growth advantage in such conditions.
Outer membrane vesicles (OMVs) from Tenacibaculum maritimum as a potential vaccine against fish tenacibaculosis.
Fish Shellfish Immunol
November 2024
Department of Microbiology and Parasitology, Aquatic One Health Research Center (iARCUS) and Faculty of Biology-CIBUS, University of Santiago de Compostela, Santiago de Compostela, Spain. Electronic address:
Outer membrane vesicles (OMVs) have been gained increasing attention in vaccinology due to their ability to induce strong protective humoral and cell-mediated immunity. The Gram-negative bacterium Tenacibaculum maritimum, the causative agent of marine tenacibaculosis, poses a significant challenge to the global aquaculture industry due to its difficult prophylaxis. In previous studies, we demonstrated that OMV production is a key virulence mechanism in T.
View Article and Find Full Text PDFDetection of Aeromonas salmonicida subsp. salmonicida infection in zebrafish by labelling bacteria with GFP and a fluorescent probe based on the siderophore amonabactin.
Microb Pathog
December 2023
CICA - Centro Interdisciplinar de Química e Bioloxía e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, 15071, A Coruña, Spain. Electronic address:
Zebrafish (Danio rerio) is an excellent model to study bacterial infections in fish and their treatment. We used zebrafish as a model of infection for Aeromonas salmonicida subsp. salmonicida (hereinafter A.
View Article and Find Full Text PDFTELEA-Farmacia: Pharmaceutical care by Telepharmacy to oncology patients from a hospital pharmacy service.
Farm Hosp
October 2022
Servicio de Farmacia, Área Sanitaria de Santiago de Compostela e Barbanza (SERGAS), Santiago de Compostela Grupo de Farmacología Clínica, Instituto de Investigación Sanitaria Santiago de Compostela (IDIS), Santiago de Compostela.
Objective: To describe the implementation of a pilot Telepharmacy project (TELEA-Farmacia) in adult patients with cancer, analyze the results obtained, and identify opportunities for improvement, from a hospital pharmacy service.
Method: Between October and December 2021, oncology patients, collecting their oral antineoplastic drugs at the Unit of Oncology Pharmacy of the hospital pharmacy service were stratified using the MAPEX model. Oncology patients candidates for inclusion in the TELEA-Farmacia project included "medium-high priority" hospital pharmacy patients, along with oncology patients who, according to pharmacist's opinion, could benefit from Telepharmacy.
Outer membrane protein FrpA, the siderophore piscibactin receptor of Photobacterium damselae subsp. piscicida, as a subunit vaccine against photobacteriosis in sole (Solea senegalensis).
Fish Shellfish Immunol
November 2019
Departamento de Microbioloxía e Parasitoloxía, Instituto de Acuicultura, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain. Electronic address:
Photobacteriosis caused by Photobacterium damselae subsp. piscicida (Pdp) remains one of the main infectious diseases affecting cultured fish in Mediterranean countries. Diverse vaccine formulations based in the use of inactivated bacterial cells have been used with unsatisfactory results, especially in newly cultured species like sole (Solea senegalensis).
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