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Effects of Spinal Cord Stimulation in Patients with Small Fiber and Associated Comorbidities from Neuropathy After Multiple Etiologies.
J Clin Med
January 2025
Research Group in Social and Nutritional Epidemiology, Pharmacoepidemiology and Public Health, Department of Preventive Medicine and Public Health, Food Sciences, Toxicology and Forensic Medicine, Faculty of Pharmacy, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain.
The aim of this study was to evaluate the effects of spinal cord stimulation (SCS) on pain, neuropathic symptoms, and other health-related metrics in patients with chronic painful peripheral neuropathy (PN) from multiple etiologies. A prospective single center observational longitudinal cohort study assessed SCS efficacy from April 2023 to May 2024, with follow-ups at 2, 4, 6, and 12 months in 19 patients suffering from the painful polyneuropathy of diverse etiologies: diabetic (DPN), idiopathic (CIAP), chemotherapy-induced (CIPN), and others. Patients were implanted with a neurostimulator (WaveWriter Alpha, Boston Scientific Corporation, Valencia, CA, USA) and percutaneous leads targeting the lower limbs (T10-T11) and, if necessary, the upper limbs (C4-C7).
View Article and Find Full Text PDFDifferences in medial temporal network intrinsic connectivity after a single bout of exercise relate to fitness, memory, and affect.
Neuroimage
January 2025
Neuropsychology and Functional Neuroimaging, Universitat Jaume I, Castellón de la Plana, Spain. Electronic address:
Introduction: Chronic exercise has been linked to structural and functional changes in the hippocampus and surrounding areas. However, less is known about how a single session of exercise can induce immediate effects that may contribute to these long-term changes.
Objective/methods: Resting-state fMRI was used to investigate changes in brain networks 19 min after a 20-min bout of vigorous-intensity acute exercise.
Uterine Repair Mechanisms Are Potentiated by Mesenchymal Stem Cells and Decellularized Tissue Grafts Through Elevated , , and Gene Expression.
Bioengineering (Basel)
December 2024
Laboratory for Transplantation and Regenerative Medicine, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.
Transplantation of decellularized uterus tissue showed promise in supporting regeneration following uterine injury in animal models, suggesting an alternative to complete uterus transplantation for uterine factor infertility treatment. However, most animal studies utilized small grafts, limiting their clinical relevance. Hence, we used larger grafts (20 × 10 mm), equivalent to nearly one uterine horn in rats, to better evaluate the bioengineering challenges associated with structural support, revascularization, and tissue regeneration.
View Article and Find Full Text PDFEfficacy of Autologous Micrografting Technology in Managing Osteoarthritis Pain: A Pilot Study.
Bioengineering (Basel)
November 2024
Fundació Hospital Sant Joan de Déu de Martorell, 08760 Barcelona, Spain.
Osteoarthritis (OA) is one of the most common joint diseases worldwide, predominantly present in elderly people. Being a major source of pain for patients, it is debilitating and leads inevitably to a reduction in quality of life. The management of OA needs a personalized and multidimensional approach, resulting in the emergence of new regenerative and non-invasive methods, such as the use of micrografts.
View Article and Find Full Text PDFPsychomotor development, emotional regulation, and executive functions in 2-years-old children after threatened preterm labour: a prospective cohort study.
Eur Child Adolesc Psychiatry
November 2024
Mental Health Research Group, Health Research Institute La Fe, Valencia, Spain.
Article Synopsis
- The study investigates the effects of threatened preterm labor (TPL) on children's development, focusing on children at 2 years old born to mothers diagnosed with TPL.
- It categorizes participants into three groups based on gestational age at delivery: Full-term, Late Preterm, and Very Preterm TPL, alongside a control group of full-term mothers and infants without TPL.
- Results indicate that TPL children, regardless of gestational age, showed poorer emotional regulation and increased inhibition issues, with Very Preterm TPL children facing even more significant challenges in psychomotor skills and executive functions.
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