Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00006324-197307000-00005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Microneedles as a Promising Technology for Disease Monitoring and Drug Delivery: A Review.
ACS Mater Au
January 2025
Department of Electronic Systems Engineering, Indian Institute of Science, Bangalore 560012, India.
The delivery of molecules, such as DNA, RNA, peptides, and certain hydrophilic drugs, across the epidermal barrier poses a significant obstacle. Microneedle technology has emerged as a prominent area of focus in biomedical research because of its ability to deliver a wide range of biomolecules, vaccines, medicines, and other substances through the skin. Microneedles (MNs) form microchannels by disrupting the skin's structure, which compromises its barrier function, and facilitating the easy penetration of drugs into the skin.
View Article and Find Full Text PDFStaggered Design of UV-Curable Polymer Microneedle Arrays with Increased Vertical Action Space.
Polymers (Basel)
January 2025
School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Recent studies have identified microneedle (MN) arrays as promising alternatives for transdermal drug delivery. This study investigated the properties of novel staggered MN arrays design featuring two distinct heights of MNs. The staggered MN arrays were precisely fabricated via PμSL light-cured 3D printing technology.
View Article and Find Full Text PDFAmide modified cellulose-g-poly acrylic acid as a supple superabsorbent for water retention and soil conditioner.
Int J Biol Macromol
January 2025
Department of Chemistry, University of Isfahan, P.O. Box 81746-73441, Isfahan, Iran. Electronic address:
Acrylamide has high hydrophilic properties due to the presence of hydrophilic amide functional groups and is frequently used to synthesize superabsorbents. However, the toxic and carcinogenic properties of acrylamide have caused environmental concerns. The main goal of this paper is the synthesis of superabsorbent with high water absorption from biodegradable and biocompatible cellulose polymer containing amide groups in the backbone of it instead of grafting harmful acrylamide monomers to cellulose.
View Article and Find Full Text PDFFuture Prospects and Regulatory Pathways for Invasome Technologies in Transdermal Drug Delivery.
Assay Drug Dev Technol
January 2025
Department of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab, India.
Enhanced Ocular Bioavailability and Prolonged Duration via Hydrophilic Surface Nanocomposite Vesicles for Topical Drug Administration.
Pharmaceutics
November 2024
Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, No. 280 University Town Outer Ring East Road, Guangzhou 510006, China.
Background: Internal ocular diseases, such as macular edema, uveitis, and diabetic macular edema require precise delivery of therapeutic agents to specific regions within the eye. However, the eye's complex anatomical structure and physiological barriers present significant challenges to drug penetration and distribution. Traditional eye drops suffer from low bioavailability primarily due to rapid clearance mechanisms.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!