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Risk Factors for Gastrointestinal Bleeding in Patients With Acute Myocardial Infarction: Multicenter Retrospective Cohort Study.
J Med Internet Res
January 2025
Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Background: Gastrointestinal bleeding (GIB) is a severe and potentially life-threatening complication in patients with acute myocardial infarction (AMI), significantly affecting prognosis during hospitalization. Early identification of high-risk patients is essential to reduce complications, improve outcomes, and guide clinical decision-making.
Objective: This study aimed to develop and validate a machine learning (ML)-based model for predicting in-hospital GIB in patients with AMI, identify key risk factors, and evaluate the clinical applicability of the model for risk stratification and decision support.
Syndromic Surveillance and Case Identification for Varicella Among Recent Immigrants: New York City, 2023.
Am J Public Health
January 2025
Melanie S. Askari is with the Epidemic Intelligence Service at the Centers for Disease Control and Prevention (CDC) and the New York City Health Department, Long Island City, NY. Robert J. Arciuolo, Olivia Matalka, Krishika A. Graham, Beth M. Isaac, Ramona Lall, Antonine Jean, and Jennifer B. Rosen are with the New York City Health Department, Bureau of Immunization, Long Island City.
To determine utility of syndromic surveillance in improving varicella case detection during an outbreak among recent immigrants to New York City (NYC). During March through August 2023, the NYC Health Department received varicella reports from routine sources and syndromic surveillance from emergency department visits with varicella as a chief complaint or discharge diagnosis. Reports were reviewed to determine if individuals met criteria for confirmed or probable varicella cases and if cases were outbreak-associated.
View Article and Find Full Text PDFComparative Analysis of In-House and Commercially Available Media for Determining the Antifungal Susceptibility Profile of Candida Species.
Cureus
December 2024
Department of Microbiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, IND.
Background The emergence of treatment-resistant species has highlighted the importance of antifungal susceptibility testing as it is difficult to determine therapeutics solely based on species identification. However, as compared to bacterial pathogens, antimicrobial susceptibility testing in fungi still remains underutilized in most clinical diagnostic microbiological services. The disc diffusion (DD) technique is reported to be easy and cost-effective and therefore can be easily incorporated as a routine method.
View Article and Find Full Text PDFImmunohistochemical Expression of HBME-1 in a Spectrum of Thyroid Neoplasms.
Indian J Endocrinol Metab
October 2024
Department of Pathology, MGM Medical College, Navi Mumbai, Maharashtra, India.
Introduction: Thyroid neoplasms are the most common malignancy of the endocrine system, representing 3.8% of new cancer cases, and it is the ninth most common cancer overall. The immuno-histochemical marker Hector Battifora Mesotheilial-1 (HBME-1) is a monoclonal antibody that now finds its diagnostic utility as a positive marker for well-differentiated thyroid carcinomas.
View Article and Find Full Text PDFMethadone metabolite (EDDP) crystals in urine: a case report.
Scand J Clin Lab Invest
January 2025
Section of Clinical Biochemistry, University of Verona, Verona, Italy.
Crystals in urinary sediment are commonly recognized structures, typically identified by a combination of crystal morphology and urine pH. In this paper, we present the first reported case of EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidene) crystals, the primary metabolite of methadone, in a 67-year-old male with hepatorenal syndrome. Routine urinalysis revealed numerous needle-shaped crystals, which prompted further investigation.
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