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Controlled PVA Release from Chemical-Physical Interpenetrating Networks to Treat Dry Eyes.
ACS Omega
January 2025
Centre for Ocular Research & Education (CORE), School of Optometry & Vision Science, University of Waterloo, 200 University Avenue West, Waterloo N2L 3G1, ON, Canada.
Dry eye disease is becoming increasingly prevalent, and lubricating eye drops, a mainstay of its treatment, have a short duration of time on the ocular surface. Although there are various drug delivery methods to increase the ocular surface residence time of a topical lubricant, the main problem is the burst release from these delivery systems. To overcome this limitation, herein, a chemical-physical interpenetrating network (IPN) was fabricated to take control over the release of poly(vinyl alcohol) (PVA), a well-known therapeutic agent used to stabilize tear film, from gelatin methacrylate (GelMA) hydrogels.
View Article and Find Full Text PDFSupramolecular Interface Buffer Layer for Stable Zinc Anode.
Small Methods
January 2025
Science Island Branch of Graduate School University of Science and Technology of China, Hefei, Anhui, 230026, P. R. China.
The aqueous zinc ion batteries (AZIBs) are chronically plagued by the inevitable side-reaction and uneven Zn planets stack. Through regulating the water activity and Zn crystal dynamics could effectively relieve those anode/electrolyte interface problems. The (2-hydroxypropyl)-β-cyclodextrin (HBCD), characterized by the excluded-volume and mitigating zinc-flux aggregation effect, is chosen as the electrolyte additive to tail the anode/electrolyte interface.
View Article and Find Full Text PDFDiagnostic-constrained fault-tolerant control of bi-directional AGV transport systems with fault-prone sensors.
ISA Trans
January 2025
Centre de Recherche en Automatique de Nancy-Lorraine University, 2 avenue de la Forêt de Haye, BP, Vandoeuvre Lès Nancy 54516, France. Electronic address:
This paper explores a novel challenge regarding bidirectional Automated Guided Vehicles (AGVs): supervisory control amidst potential sensor faults. The proposed approach uses an event-based control architecture, guided by Supervisory Control Theory (SCT), to achieve non-blocking routing of AGVs. Unlike most routing approaches assuming full event observability, this paper investigates scenarios where events might become unobservable due to sensor faults or disturbances, which may affect the supervisor efficiency.
View Article and Find Full Text PDFKnockdown-resistant mutations in head lice (Pediculus humanus capitis) collected from schoolchildren in Riyadh, Saudi Arabia.
Sci Rep
January 2025
Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Head lice infestation remains one of the most common child problems. This problem is not only attributed to the ability of head lice to spread rapidly but also because of the head lice resistance that develops from incomplete or improper treatment. Pyrethroids are a group of medications that have been widely used for the treatment of head lice.
View Article and Find Full Text PDFFactors associated with delayed referrals of patients with sepsis from primary to tertiary healthcare in Blantyre, Malawi: a qualitative study.
BMC Prim Care
January 2025
School of Global and Public Health, Kamuzu University of Health Sciences (KUHeS), Private Bag 360, Blantyre, Malawi.
Background: Sepsis is defined as invasion of pathogens into the blood stream together with the host response to this invasion. Thus, sepsis consists of the systemic inflammatory response syndrome (SIRS)caused by infection. It is a life-threatening condition that requires prompt detection and early definitive medical intervention.
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