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Isolation from Urine Culture in Hospitalised Patients: Incidence of Complicated Urinary Tract Infections and Asymptomatic Bacteriurias and Impact on Treatment of the EUCAST 2020 Update.
Antibiotics (Basel)
December 2024
Infectious Diseases Clinic, Santa Maria della Misericordia Hospital, Department of Medicine, University of Perugia, Piazzale Menghini 1, 06132 Perugia, Italy.
Urinary tract infections (UTIs) and asymptomatic bacteriurias (ABU) represent a large field of interest for antimicrobial stewardship programmes especially after 2020 EUCAST update in antimicrobial susceptibility testing interpretation and the possible related increase in carbapenems' prescription rate. The aim of this study was to evaluate the impact of the 2020 EUCAST update on antibiotic prescription in UTI due to organism and their characteristics. A retrospective observational study.
View Article and Find Full Text PDFAssociation of Bacteriuria with Hypertension Risk in Pregnant Women.
Med Sci Monit
January 2025
Department of Obstetrics and Gynecology, Padjadjaran University, Bandung, West Java, Indonesia.
BACKGROUND Urinary tract infections (UTIs) are common during pregnancy and can negatively impact maternal and neonatal health. Hypertension in pregnancy is a leading cause of maternal morbidity. UTIs can contribute to hypertension development through mechanisms like inflammation, leading to endothelial dysfunction and impaired placental development.
View Article and Find Full Text PDFDe-implementation strategy to reduce overtreatment of asymptomatic bacteriuria in the emergency department: a stepped-wedge cluster randomised trial.
Ther Adv Infect Dis
December 2024
Internal Medicine, Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Article Synopsis
- Asymptomatic bacteriuria (ASB) is the presence of bacteria in urine without urinary tract infection symptoms, and treating it is generally not helpful.
- The study aimed to lower unnecessary antibiotic treatment for ASB in emergency departments (EDs) in the Netherlands using an educational and feedback-based strategy.
- Results showed a decrease in urinalyses ordered and a reduction in treatment duration for ASB patients, but there was no significant drop in the inappropriate use of antibiotics.
Validation and generalizability of an asymptomatic bacteriuria metric in critical access hospitals.
Infect Control Hosp Epidemiol
December 2024
Division of General Internal Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
Article Synopsis
- The study aimed to adapt the Inappropriate Diagnosis of UTI (ID-UTI) measure for use in Critical Access Hospitals (CAHs), assessing its feasibility, validity, and reliability.
- Only 40% of participating CAHs met the target for case submissions, with the ID-UTI metric showing high specificity (100%) but low sensitivity (48.5%) compared to physician reviews.
- While the adapted measure was reliable (93% agreement), challenges remain in ensuring its consistent application across CAHs.
Comprehensive analysis of the bacterial spectrum for enhanced clinical insight in microbial ureteral stent colonization, uncomplicated urinary tract infections and catheter-associated urinary tract infections: a principal component analysis-based literature review.
World J Urol
December 2024
Alta Uro AG, Centralbahnplatz 6, 4051, Basel, Switzerland.
Purpose: Controversies exist regarding the prevailing spectrum of microorganisms in microbial ureteral stent colonization (MUSC) and their clinical significance. The aim of this comprehensive review is to determine the predominant microbial spectrum in patients with an indwelling ureteral stent in comparison to catheter-associated urinary tract infections (CAUTI) and uncomplicated urinary tract infections (UTI).
Methods: Google scholar, PubMed, Embase, Medline, and Cochrane literature databases were searched from inception to April 2022 to identify manuscripts on MUSC, uncomplicated UTI and CAUTI.
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