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Rare Indocyanine-Induced Anaphylactic Shock During Deep Inferior Epigastric Artery Perforator Breast Reconstruction: A Case Report.
Ann Plast Surg
February 2025
From the Department of Plastic and Reconstructive Surgery, Ewha Womans University College of Medicine, Mokdong Hospital, Seoul, Republic of Korea.
Indocyanine green (ICG) is a water-soluble green substance that is detectable through infrared cameras and emits greenish light. Approved for medical use in the 1950s, ICG has gained prominence as a real-time visualization tool. Widely recognized as a generally safe substance, ICG is applied in diverse fields.
View Article and Find Full Text PDFThe Gift of Time, How Do I Want to Spend It? Exploring Preferences for Time Allocation Among Women with and without a Breast Cancer Diagnosis.
Appl Health Econ Health Policy
December 2024
Health Systems and Health Economics, School of Public Health, Curtin University, Bentley, Perth, Australia.
Background: Women's preferences for time allocation reveal how they would like to prioritise market work, family life, and other competing activities. Whilst preferences may not always directly translate to behaviour, they are an important determinant of intention to act.
Objective: We present the first study to apply a discrete choice experiment (DCE) to investigate time allocation preferences among women diagnosed with breast cancer and women without a cancer diagnosis.
Efficacy of Subsequent Treatments After Disease Progression on CDK4/6 Inhibitors in Patients With Hormone Receptor-Positive Advanced Breast Cancer.
JCO Oncol Pract
December 2024
Medical Oncology, Yale Cancer Center, Yale University, New Haven, CT.
Purpose: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6is) combined with endocrine therapy (ET) are the standard of care in hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (aBC). Yet, disease progression remains common. In the absence of established postprogression sequencing guidelines, we conducted a pooled analysis of Kaplan-Meier (KM)-derived patient data to assess the efficacy of subsequent treatment options after disease progression on CDK4/6i therapy.
View Article and Find Full Text PDFAntibody-drug conjugates in patients with advanced/metastatic HER2-low-expressing breast cancer: a systematic review and meta-analysis.
Ther Adv Med Oncol
November 2024
Department of Medical Oncology and Hematology, University of Virginia Comprehensive Cancer Center, Charlottesville, VA, USA.
Article Synopsis
- Recent advancements in antibody-drug conjugates (ADCs) have improved outcomes for patients with HER2-low-expressing breast cancer, a group that previously lacked effective targeted therapies.
- A systematic review and meta-analysis was conducted to evaluate the effectiveness of various ADCs, including trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG), in treating HER2-low advanced or metastatic breast cancer, pulling data from multiple reputable sources.
- The findings revealed that patients treated with T-DXd had significantly better outcomes in terms of objective response rate, disease control rate, and overall survival compared to those receiving traditional treatment options, highlighting the potential of ADCs as effective therapies.
Seven Challenges in Radiology Practice: From Declining Reimbursement to Inadequate Labor Force: Summary of the 2023 ACR Intersociety Meeting.
J Am Coll Radiol
January 2025
Chief Medical Officer, Radiology Leadership Institute, American College of Radiology; Professor and Vice Chair of Radiology at University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Article Synopsis
- - The white paper highlights seven key challenges in radiology, including issues like declining reimbursement and labor shortages, which are critical for the profession’s future sustainability.
- - It emphasizes the impact of corporatization, imaging appropriateness, and burnout on radiologists, alongside the ongoing conflicts with nonphysicians and the need for improved workflow efficiency.
- - The Intersociety Summer Conference-2023 gathered experts to discuss these challenges and brainstorm potential solutions to ensure the viability of the radiology field moving forward.
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