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Small Intestinal Bacterial Overgrowth and Childhood Malnutrition: A Comprehensive Review of Available Evidence.
Nutrients
December 2024
Department of Pediatrics 1, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureș, Gheorghe Marinescu Street no 38, 540136 Târgu Mureș, Romania.
The gut microbiome is essential for children's normal growth and development, with its formation aligning closely with key stages of growth. Factors like birth method, feeding practices, and antibiotic exposure significantly shape the composition and functionality of the infant gut microbiome. Small intestinal bacterial overgrowth (SIBO) involves an abnormal increase in bacteria within the small intestine.
View Article and Find Full Text PDFRelationship between SIBO and other bowel diseases and a common eating pattern for them. Part III.
Ann Agric Environ Med
September 2024
Higher School of Health Promotion, Kraków, Poland.
Article Synopsis
- The study explores the relationship between small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS), and inflammatory bowel diseases (IBD), stressing the potential benefits of diet therapy.
- A literature review suggests that SIBO is commonly associated with IBS and shares symptoms like abdominal pain and bloating, implying potential overlaps between these conditions.
- Increasing evidence links SIBO with IBD, particularly in Crohn's disease, highlighting the need for comprehensive treatment approaches that combine medication, psychotherapy, probiotics, and tailored dietary plans.
Efficacy of Oral Acetazolamide as Add-on Diuretic Therapy in Decongestion in Patients with Heart Failure: A Study Protocol for a Randomized Controlled Trial.
J Tehran Heart Cent
January 2024
Department of Cardiac Electrophysiology, Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: Acute heart failure is a common clinical syndrome leading to hospital admission, with few evidence-based therapies for managing congestion. This trial aims to assess the efficacy of acetazolamide combined with loop diuretics in achieving decongestion among patients who fail to respond to oral diuretics and progress to acute decompensated heart failure in the absence of injectable furosemide.
Methods: This single-center, double-blind randomized controlled trial with a 1:1 allocation ratio aims to evaluate 130 patients admitted to the infusion ward.
Metabolic bariatric surgery is considered the most effective treatment for severe obesity, however it may be associated with the development of Small Intestinal Bacterial Overgrowth (SIBO) and other gastrointestinal symptoms (GIS). This study conducted a systematic review and meta-analysis to evaluate the effects of probiotics or synbiotics on GIS and SIBO in post- metabolic bariatric surgery patients. Five studies that investigated the effect of probiotics or synbiotics in the treatment of post-surgery GIS were included in the review, with three focusing on SIBO.
View Article and Find Full Text PDFEvaluation of a Novel Smart Capsule Bacterial Detection System Device for Diagnosis of Small Intestinal Bacterial Overgrowth.
Neurogastroenterol Motil
February 2025
Medical College of Georgia, Augusta University, Augusta, Georgia.
Background: There is a large unmet need for alternative, non-invasive, and accurate diagnosis of small intestinal bacterial overgrowth (SIBO). The smart capsule bacterial detection system (SCBDS) device contains a targeted sampling technology and an onboard SCBDS assay to detect metabolically active bacteria in the small intestine. Here, we evaluated the agreement of SCBDS assay with duodenal aspiration/culture ex vivo in a multicenter clinical study.
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