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Isolation and identification of a bacteriocin with antibacterial and antibiofilm activity from Citrobacter freundii.
Arch Microbiol
July 2012
Campbell Laboratory of Ophthalmic Microbiology, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Multi- and pan-antibiotic-resistant bacteria area major health challenge in hospital settings. Furthermore,when susceptible bacteria establish surface-attached biofilm populations, they become recalcitrant to antimicrobial therapy. Therefore, there is a need for novel antimicrobials that are effective against multi-drug-resistant and surface-attached bacteria.
View Article and Find Full Text PDFThe complete DNA sequence and analysis of the virulence plasmid and of five additional plasmids carried by Shiga toxin-producing Escherichia coli O26:H11 strain H30.
Int J Med Microbiol
March 2011
Eastern Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, 600 E. Mermaid Lane, Wyndmoor, PA 19038, USA.
Article Synopsis
- Shiga toxin-producing Escherichia coli (STEC) serogroup O26 is linked to serious illnesses like hemorrhagic colitis and hemolytic uremic syndrome due to virulence genes on large plasmids.
- The study identified and sequenced six plasmids in STEC O26:H11 strain H30, with the main virulence plasmid (pO26-Vir) being approximately 168 kb and containing 196 open reading frames related to pathogenicity.
- These plasmids show genetic similarities to other known STEC plasmids and include important virulence genes as well as antibiotic resistance markers, indicating a diverse genetic landscape that helps understand the evolution of STEC strains linked to severe human diseases.
Complete genome sequence of the incompatibility group I1 plasmid R64.
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September 2010
Department of Applied Physics and Chemistry, The University of Electro-Communications, Chofugaoka, Chofu, Tokyo 182-8585, Japan.
A streptomycin and tetracycline resistance plasmid R64 isolated from Salmonella enterica serovar Typhimurium belongs to the incompatibility group I1 (IncI1). The DNA sequence of the R64 conjugative transfer region was described previously (Komano et al., 2000).
View Article and Find Full Text PDFCharacterization of two cryptic Helicobacter pylori plasmids: a putative source for horizontal gene transfer and gene shuffling.
J Bacteriol
May 2002
Max von Pettenkofer Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians Universität München, Petterkoferstrasse 9A, D-80336 Munich, Germany.
Many Helicobacter pylori isolates carry cryptic plasmids of extremely variable size. In this study we analyzed two H. pylori plasmids, pHel4 and pHel5, from H.
View Article and Find Full Text PDFIn this study, pColD157, a 6.7-kb colicinogenic plasmid of enterohemorrhagic Escherichia coli (EHEC) O157:H7 strain CL40cu, was characterized by restriction mapping and determination of its complete nucleotide sequence. The sequence consists of 6,675 bp and shows a high degree of similarity to the nucleotide sequence of colicinogenic plasmids pColD-CA23 and pColK.
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