UDP-6-deoxygalactose inhibits the UDP-galactose 4-epimerase (EC 5.1.3.2) from Escherichia coli in a competitive manner with respect to the substrate UDP-galactose, giving K(i) 1.3x10(-3)m. As a substrate for the enzyme, it is transformed into UDP-6-deoxyglucose, although the reaction stops before equilibrium is attained. Possible causes of this behaviour are discussed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177484 | PMC |
| http://dx.doi.org/10.1042/bj1310421 | DOI Listing |
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