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Update on actinomycetoma treatment: linezolid in the treatment of actinomycetomas due to spp and resistant to conventional treatments.
Expert Rev Anti Infect Ther
January 2025
Dermatology Department, Brighton General Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Introduction: Mycetoma is a chronic granulomatous infection, common throughout tropical regions, and is considered a neglected disease that mostly affects impoverished populations. Mycetoma is divided into eumycetoma, caused by fungi, and actinomycetoma, caused by filamentous bacteria. Clinical presentation is distinctive, and making the diagnosis is usually not difficult; however, access to safe and effective treatments is a major challenge.
View Article and Find Full Text PDFMycetoma Leading to Effusive Constrictive Pericarditis in an Immunocompetent Individual: A Rare Encounter.
Cureus
November 2024
Cardiothoracic Surgery, Lakeland Regional Health Medical Center, Lakeland, USA.
Nocardial infections are rare but serious, often leading to systemic and cardiopulmonary complications. This is the first reported case of causing constrictive pericarditis in an immunocompetent individual. We present a 37-year-old Caucasian female patient with no significant medical history who developed pericarditis symptoms after handling crates from China.
View Article and Find Full Text PDFQuinoxaline 1,4-di--oxide Derivatives as New Antinocardial Agents.
Molecules
September 2024
Laboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Boulevard del Maestro, s/n, Esq. Elías Piña, Reynosa 88710, México.
Mycetoma is currently considered as a neglected tropical disease. The incidence of mycetoma is unknown but most of the worldwide cases are present in the "mycetoma belt" including countries like Mexico, India, Senegal, and others. The treatment of mycetoma depends on the etiological agent responsible for the case.
View Article and Find Full Text PDFA Case Report of a Mysterious Mycetoma.
Cureus
July 2024
Department of Surgery, University of Miami JFK Medical Center, Atlantis, USA.
Article Synopsis
- Mycetoma is a rare, chronic infection caused by bacteria or fungi found in soil and water, mainly affecting males in endemic areas and presenting as painless swellings that can develop into severe lesions.
- Increased immigration and travel have heightened the prevalence of mycetoma in previously unaffected regions, making early diagnosis essential to prevent serious outcomes like limb loss and septicemia.
- This case study focuses on a Guatemalan immigrant landscaper with chronic actinomycetoma, highlighting the need for awareness and prompt treatment in managing this complex condition.
Extensive mycetoma in forearm, chest and neck due to Nocardia mexicana.
J Infect Dev Ctries
June 2024
Departamento de Ecología de Agentes Patógenos. Hospital General "Dr. Manuel Gea González", Tlalpan 14080. México City, México.
Article Synopsis
- - Mycetoma is a chronic inflammatory disease affecting subcutaneous tissues and sometimes bones, often caused by bacteria from the genus Nocardia.
- - A 43-year-old male presented with extensive mycetoma lesions on his forearm, chest, and neck, showing signs such as erythema and draining pus, diagnosed through genetic sequencing which identified Nocardia mexicana.
- - Successful treatment with a combination of antibiotics was achieved after six months, and the case suggests that Nocardia mexicana can spread through contact with animals, as it was linked to the patient’s manipulation of a calf.
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