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is celebrating its first birthday and has recently reached the publication of its 100th peer-reviewed paper. We mark our transition to toddlerhood by reflecting on publications, milestones, and development.
View Article and Find Full Text PDFFitoterapia
October 2024
Department of Chemistry, Higher Teacher Training College, University of Yaoundé I, P.O. Box 47, Yaoundé, Cameroon. Electronic address:
Besides plants and animals, the fungal kingdom consists of several species characterized by various forms and applications. Fungi are amazing producers of bioactive natural products with applications in medicine and agriculture. Though this kingdom has been extensively investigated worldwide, it remains relatively underexplored in Africa.
View Article and Find Full Text PDFArterioscler Thromb Vasc Biol
July 2024
University of California San Diego, La Jolla.
In fitting with the American Heart Association’s 100th anniversary of its founding and organizing a Centennial Collection to celebrate this event, lipoprotein(a) [Lp(a)] celebrates its 61 birthday in November 2024. There has been substantial progress in understanding the biology and pathophysiology of Lp(a) in the last 6 decades, including its discovery as a unique β-lipoprotein containing the pathognomonic apolipoprotein(a) moiety covalently bound to apolipoprotein B-100, its independent monogenetic association with cardiovascular disease and calcific aortic valve disease, its increased content of pro-atherogenic and pro-inflammatory of oxidized phospholipids relative to other lipoproteins and the development of RNA therapeutics to lower plasma Lp(a) levels. The validation or refutation of the “Lp(a) hypothesis”, namely that lowering plasma Lp(a) will lead to clinical benefit, is ongoing in 3 clinical outcomes trials.
View Article and Find Full Text PDFBiol Futur
March 2024
Department of Family Medicine, SE Semmelweis University, 1085, Budapest, Stáhly u. 7-9., Budapest, Hungary.
Am J Orthopsychiatry
September 2024
Department of Psychiatry, Boston Children's Hospital.
On the 100th birthday of the , it is appropriate to reflect on the evolution of thought on depression prevention research, as seen through a historical perspective, to note how the field has grown and how it can address the issues of today. This article is a personal reflection on one practitioner's evolution of thought on resilience and preventive intervention, starting with interviewing civil rights workers, to conceptualizing self-understanding as an essential component of resilience, to the development of a family-based preventive intervention for parental depression, which was disseminated, adapted, and incorporated into a growing body of prevention research. Consensus statements on mental health prevention from the National Academies are reviewed, and the importance of a social justice perspective is highlighted throughout.
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