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Temporal serum neurofilament light chain concentrations in sheep inoculated with the agent of classical scrapie.
PLoS One
February 2024
United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Objective: Neurofilament light chain (Nf-L) has been used to detect neuroaxonal damage in the brain caused by physical injury or disease. The purpose of this study was to determine if serum Nf-L could be used as a biomarker for pre-symptomatic detection of scrapie in sheep.
Methods: Four sheep with prion protein genotype AVQQ were intranasally inoculated with the classical scrapie strain x124.
Therapeutic contact lens-related infection by a novel pathogenic fungus Coniochaeta hoffmannii-a case report.
Indian J Med Microbiol
September 2023
Biofilm and Bioprocess Laboratory, Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli-627012, Tamilnadu, India. Electronic address:
Article Synopsis
- * The patient, who had pseudophakic bullous keratopathy, experienced unexpected vision loss after four months of BCL treatment meant to alleviate pain.
- * Investigations, including a slit-lamp examination and microbial testing of the removed BCL, confirmed the presence of the fungus using Sanger sequencing for precise identification.
in a country of low incidence: a tricky diagnosis.
Hepatobiliary Surg Nutr
December 2019
Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Background: is a foodborne trematode present worldwide. Definitive hosts are mostly ruminants such as cattle and sheep, as well as humans. In Switzerland, infection in humans is rare.
View Article and Find Full Text PDFA genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression.
BMC Genomics
October 2019
Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh, Midlothian, EH26 0PZ, UK.
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide. Control relies on injectable endectocides and organophosphate dips, but concerns over residues, environmental contamination, and the development of resistance threaten the sustainability of this approach, highlighting interest in alternative control methods. However, development of vaccines and identification of chemotherapeutic targets is hampered by the lack of P.
View Article and Find Full Text PDFDraft Genome Assembly of the Sheep Scab Mite, Psoroptes ovis.
Genome Announc
April 2018
Moredun Research Institute (MRI), Edinburgh, United Kingdom.
Sheep scab, caused by infestation with , is highly contagious, results in intense pruritus, and represents a major welfare and economic concern. Here, we report the first draft genome assembly and gene prediction of based on PacBio sequencing. The ∼63.
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