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Rotating Hinge Revision Total Knee Arthroplasty With and Without Porous Cone Adjunct Fixation.
J Arthroplasty
January 2025
Georgetown University School of Medicine, MedStar Georgetown University Hospital, Washington, D.C, USA. Electronic address:
Introduction: As the number of revision total knee arthroplasties (rTKA) continues to rise, there is increasing interest in the use of contemporary rotating hinge prostheses. These devices often incorporate porous cones to fill bone defects and enhance long-term fixation. This study evaluated the clinical and functional outcomes and survivorship in rTKA patients utilizing a rotating hinge prosthesis with flexible titanium (FT) cones, porous tantalum (PT) cones, or no cones.
View Article and Find Full Text PDFComparison of the Modified CTOD Measurement Method with the Double Clip Gauge Method in a Compact Tension Specimen.
Materials (Basel)
January 2025
Smart Forming Process Group, Korea Institute of Industrial Technology, Ulsan 44776, Republic of Korea.
For allowable defect analyses, the fracture toughness of materials needs to be accurately predicted. In this regard, a lower fluctuation of fracture toughness can lead to reduction in safety and economic risks. Crack tip opening displacement (CTOD), which is the representative parameter for fracture toughness, can be measured by various methods, such as the δ5, the J-conversion method, the single clip gauge method, and the double clip gauge method.
View Article and Find Full Text PDFDiverse Interactions of Sterols with Amyloid Precursor Protein Transmembrane Domain Can Shift Distribution Between Alternative Amyloid-β Production Cascades in Manner Dependent on Local Lipid Environment.
Int J Mol Sci
January 2025
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Alzheimer's disease (AD) pathogenesis is correlated with the membrane content of various lipid species, including cholesterol, whose interactions with amyloid precursor protein (APP) have been extensively explored. Amyloid-β peptides triggering AD are products of APP cleavage by secretases, which differ depending on the APP and secretase location relative to ordered or disordered membrane microdomains. We used high-resolution NMR to probe the interactions of the cholesterol analog with APP transmembrane domain in two membrane-mimicking systems resembling ordered or perturbed lipid environments (bicelles/micelles).
View Article and Find Full Text PDFHuman talocrural contributions to ankle joint complex kinematics during walking, running, and hopping.
Heliyon
January 2025
School of Human Movement and Nutrition Science, The University of Queensland, Brisbane, Australia.
The human ankle joint complex, consisting of calcaneus, talus, and tibia, is often simplified as a single functional ankle joint, neglecting the motion of the talus. Understanding the individual contributions of the talus and calcaneus is crucial for comprehending ankle joint complex function in healthy populations, and alterations in function that may exist in clinical conditions. To achieve accurate bone kinematics, high-resolution biplanar videoradiography was used with participants engaged in walking and running (n = 9) and hopping (n = 9) with no overlap in participants.
View Article and Find Full Text PDF[The value of studying the cervical spine in craniofacial asymmetries].
Orthod Fr
January 2025
5 rue Georges Meynieu, 44300 Nantes, France
Introduction: The relationship between facial asymmetry and cervical anomaly is rarely mentioned in the diagnosis of dento-maxillo-facial orthopaedics. It is regrettable that the study of the cervical spine is often ignored in the etio-pathogenesis of these dysmorphoses, particularly in cases of facial asymmetry.
Objective: The aim is twofold: to encourage orthodontists and maxillofacial surgeons to make a systematic study of the cervical spine in craniofacial dysmorphoses and in particular craniofacial asymmetries, without claiming that they are becoming specialists in cervical spine pathology, and to introduce the necessary training in malformations of this anatomical region as part of the orthodontist specialisation curriculum.
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