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Development of a unique crosslinked glycosaminoglycan for soft tissue repair: Treatment of interstitial cystitis/bladder pain syndrome.
PLoS One
January 2025
Glycologix, Inc., 100 Cummings Center, Beverly, Massachusetts, United States of America.
Chemical modification of naturally derived glycosaminoglycans (GAGs) expands their potential utility for applications in soft tissue repair and regenerative medicine. Here we report the preparation of a novel crosslinked chondroitin sulfate (~200 to 2000 kilodaltons) that is both soluble in aqueous solution and microfilterable. We refer to these materials as "SuperGAGs.
View Article and Find Full Text PDFThe effects of preoperative glenohumeral osteoarthritis on rotator cuff repair: A systematic review and meta-analysis.
PLoS One
January 2025
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Purpose: This meta-analysis was carried out to evaluate the clinical effectiveness of rotator cuff repair surgery in treating rotator cuff tears in individuals with mild glenohumeral osteoarthritis (GHOA).
Methods: A computer-based search was conducted across multiple databases including PubMed, Embase, Web of Science, and Cochrane Library using the keywords "Shoulder Joints", "Osteoarthrosis", and "rotator cuff". Only studies focusing on patients with GHOA who underwent rotator cuff repair were considered for inclusion.
Prevalence and associated factors of postpartum anemia after cesarean delivery in public hospitals of Awi zone, North West Ethiopia, 2023; a cross-sectional study.
PLoS One
January 2025
Department of Midwifery, College of Health Sciences, Assosa University, Assosa, Ethiopia.
Background: Anemia is a serious global public health problem, especially in developing nations. Anemia during pregnancy is appropriately recognized, whereas postpartum anemia especially after cesarean delivery in Ethiopia has received very little attention. Due to this it leads to poor quality of life, palpitations, an increase in maternal infections, exhaustion, diminished cognitive function and postpartum depression.
View Article and Find Full Text PDFAssociation of Biomarkers Such as CA, TP, TES and ALP With Osteoarthritis Risk: A Mendelian Randomized Study.
Int J Rheum Dis
January 2025
Department of Orthopedics, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei, China.
Objective: Osteoarthritis is a common joint disease caused by a variety of risk factors, and it has been found that many biochemical markers are abnormal in peripheral blood and urine of patients with OA. The aim of this study was to elucidate the causal relationship between biomarkers associated with these processes and OA using Mendelian randomization (MR) analysis.
Method: The inverse variance weighted (IVW) approach to MR was primarily used to explore causal associations between exposures and outcomes using publicly available genetic variants from large genome-wide association studies (GWAS).
Influence of Unspecific Visual-Perceptual-Cognitive Task Constraints on Jump Ability and Reactive Strength in Federated Soccer Players.
Eur J Neurosci
January 2025
Faculty of Physical Activity and Sport Sciences (INEF), Sports Department, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Soccer players must react quickly and execute complex mental processes to adapt to competitive scenarios while maintaining peak physical performance. Perceptual-cognitive training methods integrate reaction tasks using nonspecific visual stimuli with game-like motor actions, but the impact on explosive strength responses is unclear. This study investigates the effect of nonspecific visual stimuli with varying perceptual-cognitive constraints on jump performance, including countermovement jump height, reactive strength index modified, action time, and reaction time.
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