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Fungal Biocontrol Agents in the Management of Postharvest Losses of Fresh Produce-A Comprehensive Review.
J Fungi (Basel)
January 2025
Gastro-Intestinal Microbiology and Biotechnology Unit, Agricultural Research Council-Animal Production, Private Bag X02, Irene, Pretoria 0062, South Africa.
Postharvest decay of vegetables and fruits presents a significant threat confronting sustainable food production worldwide, and in the recent times, applying synthetic fungicides has become the most popular technique of managing postharvest losses. However, there are concerns and reported proofs of hazardous impacts on consumers' health and the environment, traceable to the application of chemical treatments as preservatives on fresh produce. Physical methods, on the other hand, cause damage to fresh produce, exposing it to even more infections.
View Article and Find Full Text PDFInfluence of Practitioner Dashboard Feedback on Anesthetic Greenhouse Gas Emissions: A Prospective Performance Improvement Investigation.
J Med Syst
January 2025
Department of Anesthesiology, Perioperative and Pain Medicine, The Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1010, New York, NY, 10029, USA.
Article Synopsis
- Anesthetic gases are linked to global warming, prompting a project to analyze their carbon dioxide equivalent (CDE) production and fresh gas flows (FGF) in the operating room over two years.
- In the second year, individualized feedback through a dashboard significantly reduced median FGF from 2.0 to 1.9 l/min and total CDE from 5.10 to 3.59 kg/hr (both p < 0.001).
- The intervention resulted in notable reductions in CDE for isoflurane and nitrous oxide, leading to faster declines in their usage rates, although it showed no significant impact on sevoflurane or nitrous oxide CDE rates.
Conceptual foundations of a REFRAME-based approach to discriminate across total knee implant designs based on the positions of functional centres of rotation.
Sci Rep
January 2025
Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Ludwig Maximilians University Munich, Munich, Germany.
In modern knee arthroplasty, surgeons increasingly aim for individualised implant selection based on data-driven decisions to improve patient satisfaction rates. The identification of an implant design that optimally fits to a patient's native kinematic patterns and functional requirements could provide a basis towards subject-specific phenotyping. The goal of this study was to achieve a first step towards identifying easily accessible and intuitive features that allow for discrimination between implant designs based on kinematic data.
View Article and Find Full Text PDFDDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells.
Nat Commun
December 2024
Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.
Pluripotent stem cells possess a unique nuclear architecture characterized by a larger nucleus and more open chromatin, which underpins their ability to self-renew and differentiate. Here, we show that the nucleolus-specific RNA helicase DDX18 is essential for maintaining the pluripotency of human embryonic stem cells. Using techniques such as Hi-C, DNA/RNA-FISH, and biomolecular condensate analysis, we demonstrate that DDX18 regulates nucleolus phase separation and nuclear organization by interacting with NPM1 in the granular nucleolar component, driven by specific nucleolar RNAs.
View Article and Find Full Text PDFOrganic compounds in valley fogwater in North and Mount Lebanon during COVID-19 period.
Sci Total Environ
January 2025
Institute of Chemistry and Processes for Energy, Environment and Health ICPEES UMR 7515, University of Strasbourg, F-67087 Strasbourg Cedex 3, Strasbourg, France. Electronic address:
Article Synopsis
- Caltech's Active Strand Cloudwater collectors gathered valley fog samples from Mount and North-Lebanon in 2021 to analyze organic matter for the first time.
- Numerous pollutants were found in the fogwater, including pesticides, phenols, acids, and persistent organic pollutants like PCBs and PAHs.
- The study highlights strong correlations between various compounds, suggesting that vehicle exhaust and atmospheric conditions are primary sources, emphasizing the need for further research on the agricultural potential of fogwater in Lebanon.
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