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Sustainable synthesis of 1,2,3-triazoles using Cyrene as a biodegradable solvent in click chemistry.
ChemSusChem
January 2025
Universita degli Studi di Milano, Department of Chemistry, Via Golgi 19, 20133, Milan, ITALY.
The first successful synthesis of 1,2,3-triazoles using CyreneTM as a biodegradable and non-toxic solvent in click chemistry has been developed. In contrast to previous methods, this sustainable approach allows product isolation by simple precipitation in water, eliminating the need for organic solvent extractions and column chromatography purifications, thus minimizing waste consumption while reducing operational costs. The protocol, performed also at gram scale, has broad applicability and versatility, as shown with complex substrates like biologically active coumarins or triazole-linked bifunctional molecules.
View Article and Find Full Text PDFAdvantages and limitations of diagnostic procedures for zoonotic helminth infections in feces.
J Helminthol
January 2025
Far Eastern Federal University, Ayaks settlement, 10, Russkiy island, Vladivostok, Primorsky krai, 690922Russia.
Helminthiasis is a common infection in both humans and other animal populations and negatively affects the health of the host, causing a range of morbidity and even mortality, especially in young people and those with weakened immune systems. A variety of diagnostic procedures with a number of modifications are available to identify the sources of infection and to assess the epidemiological situation, the effectiveness of parasite control programs, anthelmintic treatment, and the prevention of drug resistance. These can be simple and cheap methods - for example, stool smear examination - or modern highly sensitive methods - for example, PCR analysis.
View Article and Find Full Text PDFSwift and portable detection of SC7 through RNA extraction and loop-mediated isothermal amplification using lateral flow device.
Front Microbiol
January 2025
Department of Basic Sciences, Shanxi Agricultural University, Taigu, Shanxi, China.
The soybean mosaic disease-caused by the (SMV)-significantly impacts soybean quality and yield. Among its various strains, SMV-SC7 is prevalent in China. Therefore, rapid and accurate diagnosis is deemed critical to mitigate the spread of SMV-SC7.
View Article and Find Full Text PDFMosquito ecology and behavior and malaria parasite development display marked sensitivity to weather, in particular to temperature and precipitation. Therefore, climate change is expected to profoundly affect malaria epidemiology in its transmission, spatiotemporal distribution and consequent disease burden. However, malaria transmission is also complicated by other factors (e.
View Article and Find Full Text PDFSelective attention is widely thought to be sensitive to visual objects. This is commonly demonstrated in cueing studies, which show that when attention is deployed to a known target location that happens to fall on a visual object, responses to targets that unexpectedly appear at other locations on that object are faster and more accurate, as if the object in its entirety has been visually prioritized. However, this notion has recently been challenged by results suggesting that putative object-based effects may reflect the influence of hemifield anisotropies in attentional deployment, or of unacknowledged influences of perceptual complexity and visual clutter.
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