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Fungal quorum sensing molecules as potential drugs in the treatment of chronic wounds and their delivery.
Expert Opin Drug Deliv
January 2025
Smart Materials, Istituto Italiano di Tecnologia, Genova, Italy.
Introduction: Chronic non-healing wounds have emerged as a significant global healthcare challenge. Biofilm induced wound infections has been widely acknowledged. Despite the advanced understanding of biofilm formation, the existing approaches for diagnosing biofilms in wounds remain considerably suboptimal.
View Article and Find Full Text PDFEmerging Violet Phosphorus Nanomaterial for Biomedical Applications.
Adv Healthc Mater
January 2025
State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing, 211198, P. R. China.
Violet phosphorus (VP) is a phosphorus allotrope first discovered by Hittorf in 1865, which has aroused more attention in the biomedical field in recent years attributed to its gradually discovered unique properties. VP can be further categorized into bulk VP, VP nanosheets (VPNs), and VP quantum dots (VPQDs), and chemical vapor transport (CVT), liquid-phase/mechanical/laser exfoliation, and solvothermal synthesis are the common preparation approaches of bulk VP, VPNs, and VPQDs, respectively. Compared with another phosphorus allotrope (black phosphorus, BP) that is once highly regarded in biomedical applications, VP nanomaterial (namely VPNs and VPQDs) not only exhibits tunable bandgap, moderate on/off current ratio, and good biodegradability, but shows enhanced stability and biosafety as well, allowing it to be a promising candidate for a variety of biomedical applications like antibacterial therapy, anticancer therapy, and biosensing and disease diagnosis.
View Article and Find Full Text PDFAntimicrobial activity of spp. isolated from fermented foods and their inhibitory effect against foodborne pathogens.
PeerJ
January 2025
Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Lactic acid bacteria (LAB), known for their health benefits, exhibit antimicrobial and antibiofilm properties. This study investigated the cell-free supernatant (CFS) of spp., particularly KR3, against the common foodborne pathogens , and spp.
View Article and Find Full Text PDFMicrowave-synthesized NiZrO@GNP and NiZrO3@MWCNT nanocomposites: enhanced antimicrobial efficacy against biofilms and .
3 Biotech
February 2025
Catalysis and Nanomaterials Research Laboratory, Department of Chemistry, Loyola College, Chennai, Tamil Nadu 600034 India.
Unlabelled: The persistent challenge posed by antibiotic-resistant bacteria and tuberculosis necessitates innovative approaches to antimicrobial treatment. This study explores the synthesis and characterization of NiZrO₃ nanoparticles integrated with graphene nanoplatelets (GNP) and multi-walled carbon nanotubes (MWCNT), using a microwave-assisted green synthesis route, employing fenugreek () seed extract as a gelling agent. The synthesised nanocomposites were systematically analyzed using XRD, FT-IR, Raman spectroscopy, HR-SEM and HR TEM analysis to assess structural, optical, and morphological properties.
View Article and Find Full Text PDFScientific investigation on antibacterial, antioxidant, cytotoxic effects and TLC bioautography of stem bark extracts.
J Complement Integr Med
January 2025
PKFokam Institute of Excellence, Yaoundé, Cameroon.
Objectives: Hochst, belonging to the family, is known for its ethnomedicinal values, particularly in treating various diseases in Africa. This study aimed to investigate the antibacterial, antioxidant, and cytotoxic properties of stem bark extracts, with a specific focus on assessing their bioactive potential and identifying active compounds via TLC bioautography.
Methods: The antimicrobial activity was assessed using the agar well diffusion method against selected clinical strains.
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