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The relevance of the presented topic lies in the rapid growth of complications from diseases that subsequently lead to limb amputation, as well as the problem of untimely detection of ischemic tissues. The aim of the study is to determine and explain the main progressive methods of surgical treatment of obstructive diseases of vessels of different calibers that lead to circulatory disorders and tissue necrosis. The following research methods were used in the work: statistical method, bibliographic, and bibliosemantic.

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Importance: Chronic limb-threatening ischemia (CLTI) is a major public health issue that requires considerable human and physical resources to provide optimal patient care. It is essential to characterize the disease severity and resource needs of patients with CLTI presenting to facilities of varying resource capacities.

Objective: To investigate the association between facility-level Medicaid payer proportions and the incidence of nonelective admissions among patients admitted for CLTI.

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Fournier's gangrene (FG) is a type of necrotizing fasciitis affecting the abdomen or perineum. It is a polymicrobial infection that progresses to an obliterating endarteritis, causing thrombosis and subsequent tissue necrosis, allowing pathogenic invasion of interfacial planes.Patients with Fournier's gangrene typically have underlying systemic conditions that cause vascular insufficiencies or immunosuppression.

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Fulminant non-traumatic Clostridium perfringens necrotizing fasciitis and myonecrosis in a child with acute myeloid leukemia.

J Infect Public Health

December 2024

Department of Pediatric Infectious Diseases, Ministry of National Guard-Health Affairs (MNGHA), King Abdullah Specialist Children Hospital, Riyadh,  Saudi Arabia; King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia; Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City (KAMC), MNGHA, Riyadh, Saudi Arabia.

Necrotizing fasciitis is a potentially life-threatening infection that can lead to rapid muscular and fascial necrosis, often resulting in sepsis. In addition to the rapid disease progression, diagnosing this disease in children can be challenging as they cannot accurately communicate their symptoms. Spontaneous necrotizing fasciitis secondary to Clostridial infection has rarely been described in the literature but occurs in neutropenic patients with significant morbidity and mortality from myonecrosis and gas gangrene.

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Fournier's gangrene is a grave necrotizing fasciitis that primarily affects the perineum, spreading through the fascias and leading to significant tissue destruction. The involvement of the urethra in necrosis is extremely rare, if not anecdotal. Emphysematous pyelonephritis, is a urinary infection with a high risk of progression to sepsis.

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