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Introduction: Dystrophic calcifications are the most common subtype of skin calcinosis. Tumorous soft tissue calcium deposits usually contain hydroxyapatite and amorphous calcium phosphate. Differential diagnosis of skin calcinosis encompasses Thibierge-Weissenbach syndrome, systemic sclerosis, scleroderma, CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia), dermatomyositis, systemic lupus erythematosus, ad myositis ossificans progressiva.
View Article and Find Full Text PDFFolia Med (Plovdiv)
December 2002
Department of Radiology, Medical University, 15A Vassil Aprilov St., 4000 Plovdiv, Bulgaria.
The case of a 55-year-old woman with Thieberge--Weissenbach syndrome is presented in this report. The disease was recognized as a separate diagnostic entity in 1985. This study is focused on the clinical features and the course of the syndrome.
View Article and Find Full Text PDFAnn Med Interne (Paris)
May 2002
Service de Rhumatologie, Hôpital Bichat, 46, rue Henri-Huchard, 75877 Paris Cedex 18.
CREST syndrome has been described as a form of progressive systemic sclerosis in which there is relatively limited involvement of the skin, prominence of calcinosis, Raynaud's phenomenon, esophageal dysfunction and telangiectasia. The acronym CREST was coined in 1964 by Winterbauer in the USA but the very first case report was by French physicians Thibierge and Weissenbach in 1910. Antinuclear antibodies recognizing chromosomal centromere proteins are characteristic of CREST syndrome and are present in more than 50% of the cases.
View Article and Find Full Text PDFAnn Med Interne (Paris)
January 1999
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