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Hand-Assisted Laparoscopic Surgery (HALS) as an Alternative to Unplanned Laparoscopic Conversion to Open Surgery (LCOS) in Colectomies for Acute Diverticulitis.
Surg Innov
January 2025
Morristown Medical Center, Department of Surgery, Morristown, NJ, USA.
Background: In difficult colorectal cases, surgeons may opt for a hand-assisted laparoscopic (HALS) colectomy or attempt a laparoscopic surgery that may require an unplanned conversion to open (LCOS). We aimed to compare the clinical outcomes of these 2 types of surgeries.
Methods: Colectomies for acute diverticulitis with a HALS or LCOS surgery were selected from the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) 2022 Targeted Colectomy Database.
Gender-Based Analysis of Injury Types and Risk Factors in Professional Tennis Players - Insights for Prevention: A Concise Review.
J Trauma Nurs
January 2025
Author Affiliations: NOVA Southeastern University, Kiran Patel College of Allopathic Medicine, Fort Lauderdale, Florida (Nunes Espat, Breeding, Nasef, and Amin); University of Hawaii, John A. Burns School of Medicine, Honolulu, Hawaii (Chin); Department of Surgery, Division of Trauma and Surgical Critical Care, Orlando Regional Medical Center, Orlando, Florida (Dr Elkbuli); and Department of Surgical Education, Orlando Regional Medical Center, Orlando, Florida (Dr Elkbuli).
Background: Tennis is a globally popular sport offering physical benefits but poses a high risk of injury due to its demands and prolonged gameplay. While injuries are common among professional players, detailed injury data for this group is limited.
Objective: This review aims to analyze trends in the incidence, type, region, and onset of injuries in professional tennis players, with particular attention to gender distribution, to improve guidelines and reduce injury impacts on performance and career longevity.
Revolutionizing colorectal cancer detection: A breakthrough in microbiome data analysis.
PLoS One
January 2025
Department of Computer Science, Faculty of Computing, Federal University of Lafia, Lafia, Nasarawa State, Nigeria.
Article Synopsis
- The emergence of Next Generation Sequencing (NGS) technology has transformed clinical diagnostics, providing extensive microbiome data for personalized medicine.
- Despite its potential, microbiome data's complexity and variability pose challenges for traditional statistical and machine learning approaches, including deep learning.
- The paper presents a novel feature engineering technique that combines two data feature sets, significantly improving the Deep Neural Network's performance in colorectal cancer detection, raising the Area Under the Curve (AUC) from 0.800 to 0.923, thus enhancing microbiome data analysis and disease detection capabilities.
Anxiety among cancer patients: A cross-sectional study at The University of Gondar comprehensive specialized hospital.
PLoS One
January 2025
Department of Human Anatomy, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Introduction: Anxiety is a prevalent psychological issue among cancer patients, significantly affecting their quality of life and potentially influencing treatment outcomes. This study aims to investigate the prevalence and associated factors of anxiety among cancer patients at the University of Gondar Comprehensive Specialized Hospital in Northwest Ethiopia.
Methods: A cross-sectional study design was used, involving 384 cancer patients, selected by systematic random sampling technique, from the oncology ward.
Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.
Proc Natl Acad Sci U S A
February 2025
Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
ClpXP is a two-component mitochondrial matrix protease. The caseinolytic mitochondrial matrix peptidase chaperone subunit X (ClpX) recognizes and translocates protein substrates into the degradation chamber of the caseinolytic protease P (ClpP) for proteolysis. ClpXP degrades damaged respiratory chain proteins and is necessary for cancer cell survival.
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