Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000459368 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Luciferase-based bioluminescence revealed the facilitated diffusion of D-luciferin mediated by SLC17A3.
Biochem Biophys Res Commun
January 2025
Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan. Electronic address:
SLC17A3 localized to the apical membrane of the renal proximal tubules has been implicated in the urinary excretion of drugs and endogenous/exogenous metabolites transported into the tubules by OAT1 and OAT3. Because SLC17A3 mediates the facilitated diffusion of organic anions, which requires a sensitive and rapid assay, no system has been established to evaluate its transport activity in mammalian cells. In this study, we demonstrated that the exposure of cells expressing click beetle luciferase (bLuc) and SLC17A3 to D-luciferin produces marked bioluminescence, which enables the evaluation of SLC17A3 function.
View Article and Find Full Text PDFSexual spores in mushrooms: bioactive compounds, factors and molecular mechanisms of spore formation.
Arch Microbiol
January 2025
Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Throughout the life cycle of mushrooms, countless spores are released from the fruiting bodies. The spores have significant implications in the food and medicine industries due to pharmacological effects attributed to their bioactive ingredients. Moreover, high concentration of mushroom spores can induce extrinsic allergic reactions in mushroom cultivation workers.
View Article and Find Full Text PDFA Bibliometric Analysis on the Risk Factors of Cancer.
Genes Chromosomes Cancer
January 2025
School of Geography and the Environment, University of Oxford, UK.
Given the high lethality of cancer, identifying its risk factors is crucial in both epidemiology and cancer research. This study employs a novel bibliometric analysis method, which uses the tidytext package and tidy tools in R. This approach surpasses traditional tools like VOSviewer, offering more comprehensive and complex keyword data and clearer results compared to Bibliometrix.
View Article and Find Full Text PDFFibrotic extracellular matrix preferentially induces a partial Epithelial-Mesenchymal Transition phenotype in a 3-D agent based model of fibrosis.
Math Biosci
January 2025
Department of Biomedical Engineering, Virginia Commonwealth University, 410 West Main St., Richmond, VA, 23284, USA. Electronic address:
One of the main drivers of fibrotic diseases is epithelial-mesenchymal transition (EMT): a transdifferentiation process in which cells undergo a phenotypic change from an epithelial state to a pro-migratory state. The cytokine transforming growth factor-β1 (TGF-β1) has been previously shown to regulate EMT. TGF-β1 binds to fibronectin (FN) fibrils, which are the primary extracellular matrix (ECM) component in renal fibrosis.
View Article and Find Full Text PDFToo busy with the "rat race" to have kids? Longitudinal evidence on the impact of peer grit on the fertility of reproductive-age women in China.
Econ Hum Biol
January 2025
Institute of Western China Economic Research, Southwestern University of Finance and Economics, Chengdu, China. Electronic address:
China is currently facing a notable decline in fertility rates. This research introduces a novel perspective on the factors influencing fertility among women of reproductive age, representing the first attempt to examine the impact of peer grit on female fertility. Analyzing nationally representative panel data from China and leveraging plausibly exogenous variations in peer exposure across cohorts, we find that peer grit is associated with a reduction in fertility behavior and intentions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!