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Technology and Dementia Preconference.
Alzheimers Dement
December 2024
Georgia Institute of Technology, Atlanta, GA, USA.
Background: Chronic stress promotes life-long risk for neuropsychiatric decline by increasing neuroinflammation and disrupting synaptic health and plasticity. Our lab and others have recently demonstrated that non-invasive gamma sensory stimulation (flicker) modulates immune signaling, restores microglial function, and improves cognitive performance in mouse models of Alzheimer's disease (AD). However, no research to date has studied the effects of flicker in the context of stress.
View Article and Find Full Text PDFA Comprehensive Review of Multifunctional Nanozymes for Degradation and Detection of Organophosphorus Pesticides in the Environment.
Toxics
December 2024
School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Organophosphorus pesticides are the most extensively utilized agrichemicals in the world. They play a crucial role in regulating crop growth, immunizing against pests, and improving yields, while their unregulated residues exert serious detrimental effects on both the environment and human health. Many efforts have been made in the world to monitor organophosphorus pesticides and solve the issues caused by them.
View Article and Find Full Text PDFProbiotic Microorganisms in Inflammatory Bowel Diseases: Live Biotherapeutics as Food.
Foods
December 2024
Post-Graduate Program in Food Science, Federal University of Vale of Jequitinhonha and Mucuri (UFVJM), Street MGT 367-Km 583, No. 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.
(1) Background: Inflammatory bowel diseases (IBDs) are characterized by chronic and complex inflammatory processes of the digestive tract that evolve with frequent relapses and manifest at any age; they predominantly affect young individuals. Diet plays a direct role in maintaining the gut mucosal integrity and immune function. Regarding the diet, the administration of probiotics stands out.
View Article and Find Full Text PDFBiotechnology Revolution Shaping the Future of Diabetes Management.
Biomolecules
December 2024
Discipline of Microbiology, Department XIV Microbiology, University of Medicine and Pharmacy from Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Diabetes mellitus (DM) has a millennia-long history, with early references dating back to ancient Egypt and India. However, it was not until the 20th century that the connection between diabetes and insulin was fully understood. The sequencing of insulin in the 1950s initiated the convergence of biotechnology and diabetes management, leading to the development of recombinant human insulin in 1982.
View Article and Find Full Text PDFPotential Probes for Targeted Intraoperative Fluorescence Imaging in Gastric Cancer.
Cancers (Basel)
December 2024
Department of Clinical and Experimental Medicine, University of Florence, 50139 Florence, Italy.
Gastric cancer (GC) is a malignant tumor of the gastrointestinal tract associated with high mortality rates and accounting for approximately 1 million new cases diagnosed annually. Surgery, particularly radical gastrectomy, remains the primary treatment; however, there are currently no specific approaches to better distinguish malignant from healthy tissue or to differentiate between metastatic and non-metastatic lymph nodes. As a result, surgeons have to remove all lymph nodes indiscriminately, increasing intraoperative risks for patients and prolonging hospital stay.
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