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Pulmonary Nodules After Leflunomide Therapy in Rheumatoid Arthritis: A Case Report.
Clin Case Rep
January 2025
Department of Rheumatology Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences Tehran Iran.
Rheumatoid arthritis (RA) is a systemic autoimmune disorder with both articular and extra-articular manifestations, including rare pulmonary complications. We report a case of a 65-year-old male with long-standing RA who developed multiple cavitary pulmonary nodules following prolonged leflunomide therapy. Diagnostic evaluation excluded infectious, neoplastic, and autoimmune causes.
View Article and Find Full Text PDFLong-term antibiotic prophylaxis for prevention of rheumatic fever recurrence and progression to rheumatic heart disease.
Cochrane Database Syst Rev
September 2024
Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
Background: Rheumatic fever is a non-suppurative, inflammatory sequela of group A Streptococcus pharyngitis that can occur at two to four weeks after infection. Following an episode of rheumatic fever, there is a risk of developing rheumatic heart disease (RHD) later in life that carries significant risk of morbidity and mortality. RHD remains the largest global cause of cardiovascular disease in the young (age < 25 years).
View Article and Find Full Text PDFDiagnostic Efficacy of Diffusion-weighted Imaging in Distinguishing Chronic Diffuse Sclerosing Osteomyelitis from Suppurative Osteomyelitis of the Mandible.
Magn Reson Med Sci
July 2023
Department of Radiology, Nihon University School of Dentistry at Matsudo.
Purpose: Chronic diffuse sclerosing osteomyelitis (CDSO) is a non-suppurative inflammatory bone disease diagnosed based on combined clinical, histopathological, and radiological findings. Accurate diagnosis is important since CDSO is more refractory to treatment than suppurative osteomyelitis. The purpose of this study was to determine the diagnostic efficacy of diffusion-weighted imaging (DWI) in the quantitative assessment of CDSO to distinguish it from acute suppurative osteomyelitis (ASO) and chronic suppurative osteomyelitis (CSO) of the mandible.
View Article and Find Full Text PDFSynchronous detection of multiple myeloma and acute myeloid leukemia: A diagnostic and therapeutic challenge.
J Oncol Pharm Pract
March 2021
Department of Hematology, Ankara Numune Research and Training Hospital, Ankara, Turkey.
Introduction: Synchronous detection of multiple myeloma and acute myeloid leukemia in a single patient is a rare coincidence. Treatment of these patients is still unclear, mostly based on acute myeloid leukemia strategies combined with bortezomib.
Case Report: A 72-year-old male with no medical history was investigated for pancytopenia.
[International consensus on the treatment of pediatric otitis media with effusion and current status of treatment in China].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
November 2018
International consensus on the treatment of pediatric otitis media with effusion and current status of treatment in China Summary Otitis media with effusion (OME) is a non-suppurative inflammatory disease of the middle ear characterized by middle ear effusion and hearing loss, which is common in children.The main impact of OME in children is hearing loss and cooccurring recurrent acute otitis media, which would affect speech language development. Thus OME should be highly vigilant and prompt treatment is necessary.
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