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Confocal laser endomicroscopy: a new gold standard for the assessment of mucosal healing in ulcerative colitis.
J Gastroenterol Hepatol
March 2015
Institut des Maladies de l'Appareil Digestif, CIC INSERM 04 et Service d'Hépato-Gastroentérologie, CHU de Nantes, France.
Background And Aim: Endoscopic assessment of mucosal healing in ulcerative colitis (UC) is increasingly accepted as a measure of disease activity, therapeutic goal, and the key prognostic indicator. While regular endoscopy evaluates appearance of the mucosal surface, confocal laser endomicroscopy (CLE) enables in vivo visualization of subepithelial mucosa at 1000× magnification during ongoing endoscopy. Our aims were to determine using CLE whether endoscopically normal appearing colonic mucosa in patients with UC in remission (UC-IR) has fully regenerated mucosal structures, resolved inflammation, and to identify the mechanisms.
View Article and Find Full Text PDFA rare variant angioarchitecture of upper abdomen.
Anat Cell Biol
March 2014
Department of Anatomy, M. L. N. Medical College, Allahabad, Uttar Pradesh, India.
Vascular anomalies are frequently encountered in abdomen. But they are usually asymptomatic and diagnosed accidently during angiography or surgery leading into severe complications. Thus knowledge of angioarchitecture in abdomen, whether normal or variant, is considered prerequisite for successful, uncomplicated surgeries and interventional radiology.
View Article and Find Full Text PDF[Angio-architecture of the colon in Crohn disease and ulcerative colitis. Light microscopy and scanning electron microscopy studies with reference to the morphology of the healthy large intestine].
Langenbecks Arch Chir
January 1996
Chirurgische Abteilung, Klinikum Niederberg, Velbert.
The etiology and the pathogenesis of the chronic inflammatory bowel diseases known as Crohn's disease and ulcerative colitis have not been defined. Therefore, in this study the main emphasis was placed on description of the pathologic anatomy. Disturbed blood supply and vascular disorders have been discussed as etiopathogenetic factors.
View Article and Find Full Text PDF[Massive hemorrhage caused by colonic diverticulosis].
Ann Ital Chir
December 1994
Cattedra di Chirurgia Apparato Digerente, Università di Pavia-I.R.C.C.S. Policlinico San Matteo.
Massive hemorrhage from diverticular disease of the colon is a very difficult problem in abdominal emergency surgery. The pathogenesis of bleeding colonic diverticulosis is strictly correlated to the angioarchitecture of the colonic diverticular wall. Here the vasa recta penetrate the colonic wall from the serosa to the submucosa through connective tissue septa.
View Article and Find Full Text PDF[Angioarchitecture of the ileum and colon in Crohn disease].
Zentralbl Chir
November 1992
Chirurgische Klinik, Ruhr-Universität Bochum, St. Josef-Hospital.
Vascular changes in resected bowels of Crohn's disease were examined angiographically, microangiographically, micro-preparatorily and histologically. The proper angioarchitecture of the small and the large bowel is being destroyed in the course of the ongoing inflammatory process. Dilated capillaries, destruction of the primary angioarchitecture and its replacement by an irregular, partially bizarre pattern of scar vessels with bundling of the unchanged Vasa recta as varying vessel diameters caused by obliterating secondary fibroses can be seen in advanced Crohn's disease.
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