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Edge Artificial Intelligence Device in Real-Time Endoscopy for Classification of Gastric Neoplasms: Development and Validation Study.
Biomimetics (Basel)
December 2024
Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24253, Republic of Korea.
Objective: We previously developed artificial intelligence (AI) diagnosis algorithms for predicting the six classes of stomach lesions. However, this required significant computational resources. The incorporation of AI into medical devices has evolved from centralized models to decentralized edge computing devices.
View Article and Find Full Text PDFAGA Clinical Practice Update on Screening and Surveillance in Individuals at Increased Risk for Gastric Cancer in the United States: Expert Review.
Gastroenterology
February 2025
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California.
Description: Gastric cancer (GC) is a leading cause of preventable cancer and mortality in certain US populations. The most impactful way to reduce GC mortality is via primary prevention, namely Helicobacter pylori eradication, and secondary prevention, namely endoscopic screening and surveillance of precancerous conditions, such as gastric intestinal metaplasia (GIM). An emerging body of evidence supports the possible impact of these strategies on GC incidence and mortality in identifiable high-risk populations in the United States.
View Article and Find Full Text PDFSN promote retinal pathological neovascularization through activation of EGFR, IR and IGF-1R.
Exp Eye Res
January 2025
Department of Ophthalmology, The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Key Laboratory of Eye Health & Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology &Institute of Ophthalmic Diseases, Guangxi Academy of Medical Sciences, Nanning, 530021, China. Electronic address:
Article Synopsis
- Secretoneurin (SN) is a neuropeptide linked to the neuroendocrine system and plays a role in retinal health and pathology.
- The study found that overexpression of secretogranin II (SgII) in a mouse model of Oxygen-Induced Retinopathy (OIR) resulted in increased pathological neovascularization, while reducing SgII helped alleviate this condition without affecting normal retinal development.
- The research revealed that SN promotes angiogenesis in the eye by activating specific receptors (EGFR, IR, IGF-1R) and triggering the PI3K-AKT-mTOR signaling pathway.
Background: Since it is difficult for expert endoscopists to diagnose early gastric cancer in post-eradication status, it may be critical to evaluate the stratification of high-risk groups using the advance of gastric atrophy or intestinal metaplasia. We tried to determine whether the combination of endoscopic artificial intelligence (AI) diagnosis for the evaluation of gastric atrophy could be a useful tool in both pre- and post-eradication status.
Methods: 270 -positive outpatients (Study I) were enrolled and Study II was planned to compare patients ( = 72) with pre-eradication therapy with post-eradication therapy.
Exploring the protective effect of silver nano-extract against azoxymethane induced toxicity in female reproductive organs in rats.
Heliyon
November 2024
Food Toxicology and Contaminants Department, Food Industries and Nutrition Research Institute, National Research Centre, 33 El-bohouth St., Dokki, Giza, P.O. Box.12622, Egypt.
Reproductive toxicity from food and environmental contaminants has greatly affected human life. Plants are a fundamental source of bioactive components for relieving the harmful effects of pollutants. Hydrazine metabolites pose health threats when they enter the food chain.
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