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Searching for sexually transmitted infections by midstream urine pooling after exclusion of urinary tract infection: A cost-effectiveness analysis.
Diagn Microbiol Infect Dis
January 2025
Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain. Electronic address:
We aimed to evaluate the cost-effectiveness of screening for sexually transmitted infections (STI), Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, and Trichomonas vaginalis in patients with suspected urinary tract infection (UTI) but negative urine cultures, using a pooled sampling method. A cohort of 200 patients was analyzed. A decision tree model based on cost-effectiveness was used to evaluate the following five diagnostic strategies: (A) no screening;(B) screening only men;(C) screening only women;(D) screening men and women with high leukocyte counts (>70cells/µL);(E) screening all men and women.
View Article and Find Full Text PDFinfects the urogenital tract of men and women and causes the sexually transmitted infection trichomoniasis. Since the publication of its draft genome in 2007, the genome has drawn attention for several reasons, including its unusually large size, massive expansion of gene families, and high repeat content. The fragmented nature of the draft assembly made it challenging to obtain accurate metrics of features, such as spliceosomal introns.
View Article and Find Full Text PDFMetacaspases-Like Proteases of Trichomonas vaginalis: In Silico Identification and Characterization.
J Basic Microbiol
January 2025
Laboratorio de Bioquímica y Genética Molecular, Facultad de Química, Universidad Autónoma de Yucatán, Mérida, Yucatán, México.
Metacaspases (MCA), are cysteine-dependent proteases closely related to caspases. In protozoa, MCA plays an important role in programmed cell death (PCD). In Trichomonas vaginalis, a kind of PCD that resembles apoptosis has been described, but the activators of this mechanism have not been demonstrated.
View Article and Find Full Text PDFAntimicrobial Resistance in Curable Sexually Transmitted Infections.
Curr HIV/AIDS Rep
January 2025
Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Purpose Of Review: Antimicrobial resistance in sexually transmitted infections (STIs) has become an urgent global public health threat, raising the specter of untreatable infections. This review summarizes the determinants of resistance among the five most common curable STIs Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Treponema pallidum, and Trichomonas vaginalis, as well as strategies to mitigate the spread of resistance.
Recent Findings: Genetic mutations are key drivers of resistance for N.
Parasite findings in the MacQueen's bustard, Chlamydotis macqueenii (Grey, 1832), and considerations on the parasite fauna of bustards and the systematic position of some of the parasites.
Vet Parasitol Reg Stud Reports
January 2025
Central Veterinary Research Laboratory, PO Box 597, Dubai, United Arab Emirates.
Samples from 1,254 MacQueen's bustards (Chlamydotis macqueenii) were sent for parasitological examination to the department of parasitology of the Central Veterinary Research Laboratory between 2003 and 2022. The birds originated from sanctuaries where confiscated birds were kept but also from from zoos and private collections or were bred in captivity and released to conservation areas where they got injured or died for various reasons. The material consisted of mainly of intestines and faecal samples as well as heads, stomachs, muscles samples and cysts, isolated helminths, ecto-parasites and fly larvae.
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