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Titanium particle-induced inflammasome in human gingival epithelial cells.
J Dent Sci
January 2025
Department of Periodontology, Nihon University School of Dentistry, Tokyo, Japan.
Background/purpose: Peri-implantitis remains a substantial challenge. This study investigated the effect of titanium particles on human oral epithelial cells, focusing on the nucleotide-binding domain and leucine-rich repeat protein (NLRP) 3 inflammasome.
Materials And Methods: The Ca9-22 human gingival epithelial cell line was subjected to incubation with titanium particles.
The chromosome-level genome of the ctenophore Mnemiopsis leidyi A. Agassiz, 1865 reveals a unique immune gene repertoire.
Genome Biol Evol
January 2025
Division of Marine Ecology, Marine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, Germany.
Ctenophora are basal marine metazoans, the sister group of all other animals. Mnemiopsis leidyi is one of the most successful invasive species worldwide with intense ecological and evolutionary research interest. Here, we generated a chromosome-level genome assembly of M.
View Article and Find Full Text PDFRare earth element erbium induces immune toxicity through the ROS/NF-κB pathway in zebrafish.
Fish Shellfish Immunol
January 2025
Jiangxi Province Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou, 341000, China. Electronic address:
The large-scale mining and utilization of rare earth elements have significantly increased their concentration in the environment, especially in regions surrounding mining areas. These environmentally-enriched rare earth elements accumulate in agricultural products and organisms through soil and water, potentially impacting in human health through the food chain. Erbium (Er), a rare earth element of the lanthanide series (Group IIIB), plays a crucial role in various modern technological applications.
View Article and Find Full Text PDFDeleted in malignant brain tumors 1 (DMBT1) gene relate to immune priming and phagocytosis modulation in the small abalone Haliotis diversicolor.
Comp Biochem Physiol C Toxicol Pharmacol
January 2025
Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China. Electronic address:
The small abalone (Haliotis diversicolor) is an economic shellfish cultured in the south coast of China. In recent years, the frequent occurrence of the disease has led to significant mortality in abalone farms. Deleted in malignant brain tumors 1 (DMBT1), a member of the scavenger receptor cysteine-rich (SRCR) protein family, plays an important role in host defense.
View Article and Find Full Text PDFAquaporin-5 facilitates liver regeneration following hepatectomy via ROS/GSDMD pathway.
Cell Signal
January 2025
Qingdao Central Hospital, University of Health and Rehabilitation Sciences (Qingdao Central Medical Group), No. 127th, South Siliu Road, Qingdao, Shandong 266042, China. Electronic address:
During the proliferative phase of liver regeneration, insufficient regulation of hepatocyte hydrogen peroxide (HO) overproduction can result in oxidative stress and hepatocyte death. This study aims to investigate the influence of Aquaporin 5 (Aqp5) on liver regeneration by evaluating its role in reactive oxygen species (ROS) generation and NLRP3-GSDMD-mediated pyroptosis. A 70 % partial hepatectomy (PHx) model was established in Aqp5 mice to evaluate the pathological changes in the liver.
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