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Renogrit attenuates Vancomycin-induced nephrotoxicity in human renal spheroids and in Sprague-Dawley rats by regulating kidney injury biomarkers and creatinine/urea clearance.
PLoS One
November 2023
Drug Discovery and Development Division, Patanjali Research Foundation, Haridwar, Uttarakhand, India.
Vancomycin, is widely used against methicillin-resistant bacterial infections. However, Vancomycin accumulation causes nephrotoxicity which leads to an impairment in the filtration mechanisms of kidney. Traditional herbal medicines hold potential for treatment of drug-induced nephrotoxicity.
View Article and Find Full Text PDFHepatitis C virus (HCV) infection: a systemic disease.
Mol Aspects Med
July 2008
GI & Liver Unit, DI.BI:M.I.S., Policlinico, University of Palermo, Palermo, Italy.
Hepatitis C virus (HCV) infection is a global health problem, being the second most common chronic viral infection in the world with a global prevalence of about 3% (about 180 million people). HCV is both an hepatotropic and a lymphotropic virus; and chronic infection could cause, on one hand, chronic hepatitis, cirrhosis and hepatocellular carcinoma and on the other hand several extrahepatic diseases including, first, mixed cryoglobulinemia and lymphoma. The association between hepatic (hepatocellular carcinoma) and extrahepatic (lymphoma, thyroid cancer) malignancies has justified the inclusion of HCV among human cancer viruses.
View Article and Find Full Text PDFTwelve-year clinico-therapeutic experience in pemphigus: a retrospective study of 54 cases.
Int J Dermatol
October 2005
Department of Dermatology, Venereology & Leprosy, Indira Gandhi Medical College, Shimla, India.
Background: Pemphigus, a common immunobullous disease of skin and mucous membranes affecting both sexes of all ages, was almost fatal before the advent of corticosteroids. Better strategies to avoid their side-effects and recent introduction of adjuvant therapy has further improved its prognosis. As the treatment remains need-based and patient-specific, different regimens and strategies have evolved, each with its own merits and demerits.
View Article and Find Full Text PDF[Urticaria in children--the current etiopathogenetic and clinico-therapeutic aspects].
Rev Med Chir Soc Med Nat Iasi
May 2000
Clinica de Pediatrie, Spitalul Clinic de Copii Dr. Victor Gomoiu, Universitatea de Medicină şi Farmacie Carol Davila, Bucureşti.
The authors present actualized data regarding urticaria, which is frequently encountered in children. The first part presents the etiology, pathogenesis and pathological aspects of urticaria. Next, are discussed clinical and paraclinical data, useful for the diagnosis.
View Article and Find Full Text PDF[Adenocarcinoid of the appendix: a case report and anatomo-pathological and clinico-therapeutic considerations].
G Chir
April 1998
Cattedra di Semeiotica Chirurgica I, Università degli Studi di Genova.
The Authors underline the most important pathological, clinical and therapeutic aspects of appendiceal adenocarcinoid. Appendiceal adenocarcinoid is quite a rare tumor, presently considered as a single entity; it differs from typical carcinoid of the appendix because of its well definite histology, its aggressive behaviour and its poorer prognosis. There are no precise prognostic and therapeutic criteria to direct the operative choice between appendectomy and hemicolectomy.
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