Two tests are described for detecting antibody to the type-specific opacity factor (OF) of group A streptococci. This antibody was detected among patients convalescent from streptococcal sore throat in two communities in which outbreaks due to opacity factor-producing strains of group A streptococci occurred.In an outbreak due to streptococci of M-type 22 there was a close correspondence between the distribution of anti-OF and of bactericidal M-antibody for the type. In a smaller outbreak due to M-type 58 streptococci, however, M-antibody was detected more often than antibody to OF.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2130433 | PMC |
| http://dx.doi.org/10.1017/s0022172400046180 | DOI Listing |
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