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Contact Lenses in Therapeutic Care: A Comprehensive Review of Past Innovations, Present Applications, and Future Directions.
Adv Exp Med Biol
January 2025
Department of Optometry, University of Benin, Benin City, Nigeria.
Contact lenses have become integral tools in the realm of ocular therapeutics, extending beyond their primary function of refractive correction to encompass a diverse array of therapeutic applications. This review explores the evolving role of contact lenses in managing various ocular conditions, highlighting their efficacy in enhancing patient outcomes. Initially developed to correct refractive errors, contact lenses now serve as effective vehicles for delivering medications directly to the ocular surface, offering targeted treatment for conditions such as dry eye syndrome and corneal ulcers.
View Article and Find Full Text PDFDiagnostics and Therapy for Malignant Tumors.
Biomedicines
November 2024
Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.
Malignant tumors remain one of the most significant global health challenges and contribute to high mortality rates across various cancer types. The complex nature of these tumors requires multifaceted diagnostic and therapeutic approaches. This review explores current advancements in diagnostic methods, including molecular imaging, biomarkers, and liquid biopsies.
View Article and Find Full Text PDFRisk factors for complications from challenging lower third molar extractions in tertiary hospital patients.
Acta Odontol Scand
December 2024
Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland; Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Helsinki, Finland.
Objective: Third molar extraction is a common procedure with occasional complications. This study aimed to determine the incidence and types of complications in challenging lower third molar extractions and to identify complication risk factors in tertiary hospital patients.
Material And Methods: A retrospective cohort study was conducted on 354 patients who underwent unilateral lower third molar extraction during a 2-year period in 2018-2019 at Helsinki University Hospital.
SUCRALFATE MAY BE AN EFFECTIVE TOPICAL AGENT IN PREVENTING ORAL MUCOSITIS.
J Evid Based Dent Pract
December 2024
Article Title And Bibliographic Information: Coppini M, Caponio VCA, Mauceri R, Bizzoca ME, Laino L, Lorenzo-Pouso AI, Russo D, Troiano G, Silva FFVE, Lo Muzio L, Campisi G. Efficacy of topical agents in oral mucositis prevention: Systematic review and network meta-analysis. Oral Dis.
View Article and Find Full Text PDFQuantifying synthetic bacterial community composition with flow cytometry: efficacy in mock communities and challenges in co-cultures.
mSystems
January 2025
Ghent University, Center for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Gent, Belgium.
Article Synopsis
- The study examines the effectiveness of flow cytometry as a quick and cost-effective method for determining the composition of synthetic bacterial communities compared to traditional methods like bacterial plating, strain-specific qPCR, and 16S rRNA gene amplicon sequencing.
- Flow cytometry showed a lower average error when quantifying the composition of axenic cultures and mock communities, outperforming both PCR-based methods and sequencing.
- However, when bacteria were co-cultured, the accuracy of all methods decreased, highlighting the difficulties in accurately quantifying community composition due to the changing phenotypes of the bacteria.
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