Vulvectomy.

Am J Nurs

Published: March 1974

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Vulvar cancer, particularly squamous cell carcinoma (SCC) and melanoma, poses significant diagnostic and therapeutic challenges due to its complex presentation and high rates of postoperative complications. Effective management requires a multidisciplinary approach, integrating the expertise of gynecologic oncologists, dermatologists, plastic surgeons, and other specialists. This review highlights the dermatologist's role in supporting early diagnosis, addressing predisposing conditions such as lichen sclerosus, and managing postoperative wound complications, including surgical site infections and dehiscence.

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Article Synopsis
  • Vulval cancers are rare, constituting only 0.25% of global cancer cases, and the COVID-19 pandemic worsened the situation by complicating proper investigations and treatment follow-ups.
  • During the pandemic, 20 non-metastatic carcinoma vulva patients underwent individualized surgeries, with follow-ups conducted every two months, adapting procedures to COVID-related challenges.
  • Results showed 85% disease-free survival at 18 months, comparable to pre-pandemic outcomes, suggesting that cancer surgery and care can be effectively managed even during significant health crises.
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Application of Negative-Pressure Wound Therapy in Patients with Wound Complications after Flap Repair for Vulvar Cancer: A Retrospective Study.

Adv Skin Wound Care

December 2024

Liangzhi Qiu, MSN, RN; Xianrong Wu, BSN, RN; and Xiu Wang, BSN, RN are Nurses Certified in Wound, Ostomy, and Continence, Chronic Wound and Ostomy Department, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. The authors have disclosed no financial relationships related to this article. Submitted October 19, 2023; accepted in revised form June 24, 2024.

Objective: To analyze the characteristics of postoperative wound complications (WCs) in patients following vulvectomy with flap repair and evaluate the efficacy of negative-pressure wound therapy (NPWT) in wound healing.

Methods: This study retrospectively reviewed 17 patients with WCs following vulvectomy with flap repair at a tertiary comprehensive hospital from January 2016 to December 2022. All patients were treated with NPWT, and the wound healing rate, healing time, and NPWT-related complications were observed.

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Well-differentiated squamous cell carcinoma of the clitoris: a rare case report.

Pan Afr Med J

December 2024

Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India.

Article Synopsis
  • Squamous cell carcinoma (SCC) can affect various organs, including the vagina and vulva, with vulvar carcinoma being a rare occurrence, typically seen in those over 70 years old, with a low prevalence of 2.6 per 100,000 people.
  • This case study focuses on a 65-year-old woman diagnosed with well-differentiated squamous cell carcinoma (WDSCC) of the clitoris, highlighting an increasing trend of diagnoses in women aged 35 to 45.
  • Current treatment approaches are shifting from radical surgeries, such as vulvectomy and lymph node removal, to more personalized and less invasive strategies for managing vulvar carcinomas.
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Impact of age on surgical excision margins for vulvar squamous cell carcinomas: A multicenter study by the francogyn group.

Surg Oncol

November 2024

ECEVE U1123, National Institute of Health and Medical Research, Paris Cité University, Paris, France; Department of Obstetrics and Gynaecology, Lariboisiere University Hospital, University Paris Cité, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.

Article Synopsis
  • Vulvar cancer primarily affects older women and requires surgical treatment, with guidelines emphasizing the importance of negative histological margins.
  • A study analyzed the impact of patient age on surgical outcomes, finding that older patients (≥65 years) had larger tumors but similar rates of negative excision margins compared to younger patients (<65 years).
  • Results indicated that younger patients experienced better recurrence-free survival and were more likely to undergo revision surgery despite the older group receiving more radical surgery.
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