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Keratin nanoparticles derived from feather waste for novel antibacterial delivery.
Int J Biol Macromol
January 2025
Biomaterials Department, Institute of Industrial Nanomaterials, Kumamoto University, Kumamoto 860-8555, Japan. Electronic address:
The global rise of bacterial resistance demands innovative strategies to enhance antibiotic efficacy. This study investigates keratin nanoparticles (KNPs) derived from waste chicken feathers as sustainable drug carriers. Antibacterial activity of KNPs was evaluated against Staphylococcus aureus and Escherichia coli using antibacterial sensitivity assays, including disc diffusion and minimum inhibitory concentration tests, while cytotoxicity was evaluated on human lymphoma cells.
View Article and Find Full Text PDFPenicillin G detection is of great significance in medical research and disease diagnosis. Liquid crystal (LC), as a branch of sensitive materials, has a broad application prospect in the field of biosensing. Herein, a liquid crystal-coated silica microbubble resonator (LC-MBR), with high sensitivity for penicillin G detection, has been proposed and demonstrated.
View Article and Find Full Text PDFEmerging epidemic of the Africa-type plasmid in penicillinase-producing in Guangdong, China, 2013-2022.
Emerg Microbes Infect
December 2025
Dermatology Hospital, Southern Medical University, Guangzhou, People's Republic of China.
The prevalence of penicillinase-producing (PPNG) is a crucial public health concern because of its resistance to penicillin and cephalosporins. From 2013 to 2022, a total of 1748 isolates from Guangdong, China, were examined for their antibiotic susceptibility and molecular epidemiological characteristics. PPNG prevalence increased markedly from 37.
View Article and Find Full Text PDFCoexistence of the blaZ gene and selected virulence determinants in multidrug-resistant Staphylococcus aureus: insights from three Nigerian tertiary hospitals.
BMC Infect Dis
November 2024
Department of Pharmaceutical Microbiology, University of Ibadan, Ibadan, Oyo State, Nigeria.
Background And Purpose: Infections caused by β-lactamase-producing strains of Staphylococcus aureus have become increasingly difficult to treat due to the expression of multiple virulence factors. This has heightened concerns about managing S. aureus-related infections.
View Article and Find Full Text PDFSynergistic potential of Leu-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus.
BMC Microbiol
October 2024
Department of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC, 3010, Australia.
Staphylococcus aureus (S. aureus) is a significant Gram-positive opportunistic pathogen behind many debilitating infections. β-lactam antibiotics are conventionally prescribed for treating S.
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