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At least four groups of kratom consumers in the United States: latent-class analysis of motivations for kratom use.
Am J Drug Alcohol Abuse
January 2025
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kratom is a plant with alkaloids acting at opioid, serotonergic, adrenergic, and other receptors. Consumers report numerous use motivations. To distinguish subgroups of kratom consumers by kratom-use motivations using latent-class analysis.
View Article and Find Full Text PDFPreoperative Resilience as a Predictor of Postoperative Regret and Patient-Reported Outcomes in Total Knee Arthroplasty.
J Am Acad Orthop Surg
January 2025
From the Department of Orthopaedic Surgery, Kaiser Permanente San Diego Medical Center, San Diego, CA (Horan), the Department of Orthopaedic Surgery, Summit Orthopedics, Eagan, MN (Baer), Shiley Center for Orthopaedic Research and Education (SCORE) at Scripps Clinic, La Jolla, CA (Shah), Georgetown University School of Medicine, Washington, DC (Shah), and the Department of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA (Wilde, Copp, and Bugbee).
Background: Total knee arthroplasty (TKA) is a well-established treatment option for advanced knee osteoarthritis, yet some patients remain unsatisfied after surgery. Evaluation of various psychosocial parameters may improve patient optimization and outcomes. The primary aim was to assess whether preoperative resilience remained stable and influenced decision regret postoperatively while the secondary aim was to evaluate its correlation with joint-specific and global health patient-reported outcome measures.
View Article and Find Full Text PDFComparison of clinical efficacy of different internal fixation methods in older adult patients with osteoporotic fractures of proximal humerus.
Front Surg
January 2025
Department of Orthopedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Objective: To compare the efficacy of three treatment methods for older adult patients with osteoporotic proximal humerus fractures: proximal humerus locking plate (PHILOS) combined with calcium sulfate injection, PHILOS plate alone, and artificial hemi-shoulder joint replacement.
Methods: The clinical data of 48 older adult patients with osteoporotic proximal humerus fractures admitted to the Shoulder and Elbow Surgery Department of Zhongshan Hospital Affiliated with Dalian University from February 2018-August 2021 were retrospectively analyzed. The patients comprised 18 males and 30 females, with a mean age of (68.
Evaluation of machine learning techniques for real-time prediction of implanted lower limb mechanics.
Front Bioeng Biotechnol
January 2025
Center for Orthopaedic Biomechanics, University of Denver, Denver, CO, United States.
Introduction: Accurate prediction of knee biomechanics during total knee replacement (TKR) surgery is crucial for optimal outcomes. This study investigates the application of machine learning (ML) techniques for real-time prediction of knee joint mechanics.
Methods: A validated finite element (FE) model of the lower limb was used to generate a dataset of knee joint kinematics, kinetics, and contact mechanics.
Background And Purpose: The introduction and development of new total knee arthroplasty (TKA) implant designs are industry driven. To date, an adequately powered randomized controlled trial (RCT) to provide evidence of the superiority of novel implant designs over conventional ones is often lacking. The aim of our RCT was to investigate the functional outcomes of a novel TKA implant design compared with 2 conventional TKA designs.
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