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Fragmentation of pulmonary emboli: in vivo experimental evaluation of two high-speed rotating catheters.
Cardiovasc Intervent Radiol
October 1996
Department of Diagnostic Radiology, University of Technology Aachen, Pauwelsstrasse 30, D-52057 Aachen, Germany.
Purpose: To test two over-the-wire systems for fragmentation of pulmonary emboli.
Methods: In 11 dogs, 22 embolic occlusions of lobar or central pulmonary arteries were performed by injection of preformed emboli through a jugular vein sheath. A commercially available device (thrombolizer) and a modified version of the impeller catheter were introduced via the femoral vein and positioned at the embolus site.
[The diagnosis and fragmentation therapy of acute massive pulmonary embolism with a rotatable pigtail catheter: experimental studies].
Rofo
November 1995
Klinik für Radiologische Diagnostik, Klinikum der RWTH Aachen.
Purpose: A dedicated pigtail catheter system which allows angiographic documentation and adjunctive mechanical fragmentation of pulmonary emboli was evaluated in an animal experiment.
Material And Method: The 5-F catheter provided with an oval side hole proximal to the pigtail tip was rotated manually or with an electric drive, and with the wire as a rotation axis. Pulmonary embolic occlusions were recanalized in ten dogs.
Direct visualization and measurement of microsurgically induced thromboembolism.
Microsurgery
December 1994
Institute of Experimental Clinical Research, Aarhus University Hospital, Skejby, Denmark.
A common cause of free flap and replant failure is thrombotic occlusion of the anastomosed pedicle vessel(s). Clinical observations and subsequent experimental studies showed that platelet emboli generated at the arterial anastomosis caused significant alterations in the downstream microcirculation. To study both the thrombogenic arterial (anastomosis) site and the downstream microcirculation, we developed an animal model (the isolated rat cremaster) in which we could directly view and quantitatively analyze thrombus formation and the appearance of emboli in the downstream microcirculation.
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