Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Treatment for osteoporosis in people with beta-thalassaemia.
Cochrane Database Syst Rev
May 2023
Department of Orthopaedics, Manipal University College Malaysia (MUCM), Melaka, Malaysia.
Background: Osteoporosis is characterized by low bone mass and micro-architectural deterioration of bone tissue leading to increased bone fragility. In people with beta-thalassaemia, osteoporosis represents an important cause of morbidity and is due to a number of factors. First, ineffective erythropoiesis causes bone marrow expansion, leading to reduced trabecular bone tissue with cortical thinning.
View Article and Find Full Text PDFMilk-Alkali Syndrome: How Electronic Medical Record Open Notes Helped to Rule Out Cancer.
Am J Case Rep
September 2022
Department of Critical Care, UPMC Central Pa, Harrisburg, USA.
BACKGROUND Milk-alkali syndrome is caused by excessive consumption of calcium and absorbable alkali and typically presents as a triad of hypercalcemia, acute renal failure, and metabolic alkalosis. In the era of histamine receptor blockers and proton pump inhibitors, the incidence of milk-alkali syndrome has decreased. However, the disease has not been eliminated, due to existing calcium-containing therapies.
View Article and Find Full Text PDFTyrosine 12 of human calcitonin modulates its amyloid formation, membrane binding, and bioactivity.
Biochimie
June 2022
Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan. Electronic address:
Irreversible aggregation greatly limits the bioavailability and therapeutic activity of peptide-based drugs, so preventing protein or peptide aggregation is a common issue in drug formulation. Human calcitonin (hCT), a peptide hormone secreted by thyroidal parafollicular cells, can regulate blood calcium levels and maintain bone structure. Hence, it can be used as a treatment for metabolic bone diseases, such as osteoporosis and Paget's disease.
View Article and Find Full Text PDFMetastatic medullary thyroid carcinoma presenting as ectopic Cushing's syndrome.
Endocrinol Diabetes Metab Case Rep
April 2021
Department of Endocrinology, Mater Misericordiae University Hospital, Dublin, Ireland.
Summary: A 41-year-old male presented to the Emergency Department with a 6-month history of back and hip pain. Skeletal survey revealed bilateral pubic rami fractures and MRI of the spine demonstrated multiple thoracic and lumbar fractures. Secondary work up for osteoporosis was undertaken.
View Article and Find Full Text PDFA qualitative process evaluation of the introduction of procalcitonin testing as an antimicrobial stewardship intervention.
Int J Clin Pharm
June 2021
Pharmacy Department, Mercy University Hospital, Grenville Place, Cork, Ireland.
Background Successful antimicrobial stewardship interventions are imperative in today's environment of antimicrobial resistance. New antimicrobial stewardship interventions should include qualitative analysis such as a process evaluation to determine which elements within an intervention are effective and provide insight into the context in which the intervention is introduced. Objective To assess the implementation process and explore the contextual factors which influenced implementation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!