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Multifaceted delineation of atrophic thyroiditis among pediatric population: An extensive literature survey.
Clin Pediatr Endocrinol
January 2025
Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan.
Autoimmune hypothyroidism is categorized into Hashimoto thyroiditis (HT) and atrophic thyroiditis (AT). Although a consensus exists among Japanese endocrinologists that pediatric AT is associated with severe hypothyroidism, the question remains whether AT and HT are separate conditions. To investigate the clinical characteristics of pediatric AT, we conducted a comprehensive literature review using PubMed and ICHUSHI, a local database.
View Article and Find Full Text PDFShort- to medium-term follow-up of normoponderal children and adolescents with subclinical hypothyroidism: a retrospective study of the last 15 years.
J Pediatr Endocrinol Metab
January 2025
School of Medicine, University of Minho, Braga, Portugal.
Objectives: Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) levels (>5 mUI/L) and normal total and free thyroxine levels (fT4). There is ongoing debate over whether mild SCH should be treated. This study aims to assess the clinical course of normoponderal pediatric patients with SCH.
View Article and Find Full Text PDFSarcoidosis is an immune-mediated multisystem condition of unknown etiology, characterized by non-caseating granulomatous inflammation. While it commonly affects the lungs and the reticuloendothelial system, it can affect any organ. Most of such cases involve the central nervous system, but the condition rarely presents with symptoms related to hypothalamic-pituitary dysfunction.
View Article and Find Full Text PDFIntracranial hypertension as the first manifestation of systemic lupus erythematosus: A case report.
Heliyon
October 2024
Universidad Icesi, CIRAT: Centro de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional, Calle 18 No. 122 -135, Cali, Colombia.
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple systems and organs, including the central and peripheral nervous systems. Papilledema and idiopathic intracranial hypertension, in the absence of space-occupying lesions or other detectable causes, is a rare manifestation. We report the case of a young woman with chronic headache, papilledema, and intracranial hypertension on examination, in whom a de novo diagnosis of systemic lupus erythematosus and class V lupus nephritis was made.
View Article and Find Full Text PDF"Exploring The Nexus": Chronic musculoskeletal pain in diabetic vs non-diabetic population.
J Orthop
May 2025
Department of Orthopaedics and Spine Surgery, Ganga Medical Center & Hospital, Coimbatore, India.
Article Synopsis
- - The study investigates the prevalence of chronic musculoskeletal pain (cMSK) in individuals with type 2 diabetes mellitus (DM) and how it relates to blood sugar control, finding that cMSK pain affects 27.7% of diabetic patients compared to 19% in healthy individuals.
- - Data was collected from 300 diabetic patients and an equal number of healthy controls, with analysis focused on blood sugar levels, clinical history, and comorbidities; results revealed a significant link between cMSK pain and higher HbA1c levels.
- - The research underscores the need to pay attention to musculoskeletal pain in diabetic patients, despite no significant associations being found with other health conditions like hypertension or hypothy
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