AI Article Synopsis
- Acetylsalicylic acid's pain-relieving and fever-reducing effects are enhanced when applied after peloid skin treatments at 42 degrees Celsius.
- The sedative effects of phenobarbital increase, while butadion shows no change in effectiveness during the same conditions.
- Ethazol's inhibitory action on the microsomal system is altered when exposed to physical treatments, affecting how the body processes and responds to various drugs.
Article Abstract
The analgetic and antipyretic action of acetylsalicylic acid is potentiated, whereas that of butadion and amidopyrine is decreased in the conditions of prior action of peloid skin applications (body temperature 42 degrees C). The effect of phenobarbital rises and that of butadion remains unchanged, whereas the inhibitory effect of ethazol revealed in the course of investigations of levelled under conditions of the action of the physical factor on the microsomal system. This leads to the changes in biotransformation and pharmacodynamics of the drugs.
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