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Atrial fibrillation (AF) has emerged as a major global cardiovascular disease in the 21st century. In China, there are greater than 12 million patients with AF, and its incidence continues to rise. AF affects patients' quality of life and significantly increases the risks of mortality, stroke, heart failure, cognitive impairment, and dementia.

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  • Intracardiac masses, like myxomas, can sometimes be identified following a stroke, but distinguishing them through echocardiography can be challenging.
  • A case study involved a 58-year-old man with various health issues who suffered an ischemic stroke; his echocardiogram showed a large mass in the left atrium, leading to a diagnosis of myxoma after surgery.
  • Myxomas may not show symptoms for a long time and can be linked to embolic complications, emphasizing the need for a comprehensive, team-based management approach.
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Left atrial appendage aneurysm: a descriptive systematic review of 177 cases.

BMC Cardiovasc Disord

November 2024

Department of Physiology, Pharmacology, and Toxicology, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

Introduction: The left atrial appendage (LAA) is a distinct structure with unique developmental and structural characteristics. The LAA is involved in the formation of intra-atrial thrombi, particularly in patients with conditions such as atrial fibrillation and mitral valve disease. Left atrial appendage aneurysms (LAAA) are rare abnormal dilations of the LAA that may cause hazardous complications.

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  • Pulmonary vein isolation (PVI) effectively manages paroxysmal atrial fibrillation (PAF), and this study investigates how P wave parameters from ECG can predict PVI success.
  • The research involved 211 patients undergoing first-time PVI, measuring various P wave metrics before the procedure, and found that specific parameters correlated with successful outcomes at 12 months.
  • Key predictors of PVI failure included increased corrected P wave duration (PWDc), decreased P wave amplitude (PWV) and area (PWA), and intra-atrial block (IAB), while P wave dispersion (PWDisp) and terminal force in V1 (PTFV1) didn’t show significant correlation.
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  • About 5% of Wilms tumors involve vascular extension, requiring a complex surgical approach that influences management but not prognosis.
  • A study of 69 pediatric patients with Wilms tumors revealed significant findings, including a 37.5% rate of right atrial extension and complications like pulmonary embolism.
  • Despite challenges, the use of neoadjuvant chemotherapy led to a high overall survival rate of 89%, though postoperative renal insufficiency was identified as a risk factor for reduced survival.
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