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Advances in radiofrequency ablation: mechanism of action and technology.
Ann Palliat Med
July 2024
Department of Anesthesiology, Mayo Clinic, Phoenix, AZ, USA.
Article Synopsis
- Radiofrequency ablation (RFA) is a minimally invasive treatment that uses high-frequency energy to precisely destroy targeted tissues, initially introduced in the early 1900s and has since evolved significantly.
- Recent advancements, such as multi-electrode systems and image-guided techniques, have improved RFA's efficacy and expanded its use for various conditions like tumors and chronic pain.
- RFA offers advantages over traditional surgery, including more precise targeting, fewer complications, and quicker recovery, making it a promising option for patient care and outcomes.
Efficacy and safety of 3D reconstruction and basket multi-electrode renal denervation (RDN) for refractory hypertensive patients with chronic kidney disease.
J Clin Hypertens (Greenwich)
April 2024
Department of Cardiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Renal Artery Sympathetic Denervation (RDN) can lower blood pressure. Different ablation catheters (single electrode, multi-electrode) have different scopes of ablation (renal artery main stem and branches). Few studies have compared the advantages and disadvantages of different ablation catheters and different procedures in terms of antihypertensive efficacy.
View Article and Find Full Text PDFEffect of high-frequency stimulation on the complexity of low-Mg-induced epileptiform discharge rhythm waves in the CA3 region of rat hippocampal slices.
Biochem Biophys Res Commun
September 2023
School of Life Sciences, Tiangong University, Tianjin, 300387, China. Electronic address:
High-frequency stimulation (HFS) is a crucial therapeutic approach for neurodegenerative conditions, such as epilepsy. However, its underlying mechanism of inhibition remains unclear. In this study, a rat model of epileptiform discharges (EDs) was constructed by perfusing brain slices with magnesium-free artificial cerebrospinal fluid (aCSF), where after HFS was used to stimulate the CA3 area of the hippocampus.
View Article and Find Full Text PDFSevoflurane Improves Ventricular Conduction by Exosomes Derived from Rat Cardiac Fibroblasts After Hypothermic Global Ischemia-Reperfusion Injury.
Drug Des Devel Ther
June 2023
School of Anesthesia, Guizhou Medical University, Guiyang, People's Republic of China.
Purpose: This study investigated the effect of exosomes derived from sevoflurane-treated cardiac fibroblasts (Sev-CFs-Exo) on reperfusion arrhythmias (RA), ventricular conduction, and myocardial ischemia-reperfusion injury (MIRI).
Methods: Primary cardiac fibroblasts (CFs) were isolated from the hearts of neonatal rats and identified by morphology and immunofluorescence. Exosomes were isolated from CFs at passages 2-3 after they had been treated with 2.
Real-Time Monitoring Using Multiplexed Multi-Electrode Bioelectrical Impedance Spectroscopy for the Stratification of Vascularized Composite Allografts: A Perspective on Predictive Analytics.
Bioengineering (Basel)
March 2023
Bioelectronics, Biosensors and Biochips (C3B®), Department of Biomedical Engineering, Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.
Vascularized composite allotransplantation addresses injuries to complex anatomical structures such as the face, hand, and abdominal wall. Prolonged static cold storage of vascularized composite allografts (VCA) incurs damage and imposes transportation limits to their viability and availability. Tissue ischemia, the major clinical indication, is strongly correlated with negative transplantation outcomes.
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