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Optimising medium chain carboxylate production in xylan mixed-culture monofermentation.

Bioresour Technol

January 2025

CRETUS, Department of Chemical Engineering, Universidade de Santiago de Compostela 15782 Santiago de Compostela, Spain.

This work investigates the optimization of medium-chain carboxylate (MCC) production through xylan mixed-culture monofermentation. The pH screening in batch assays showed that the hydrolysis stage and selectivity towards MCC precursors were optimised at pH 6. Subsequently, a continuous stirred tank reactor (CSTR) and a Sequential Batch Reactor (SBR) were operated at different Hydraulic Retention Times (HRT), revealing that the SBR at HRT 2 days yielded the highest caproic acid since lactic acid availability and chain elongation process were balanced.

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Tensor neural networks for high-dimensional Fokker-Planck equations.

Neural Netw

January 2025

Division of Applied Mathematics, Brown University, Providence, RI 02912, USA; Advanced Computing, Mathematics and Data Division, Pacific Northwest National Laboratory, Richland, WA, United States. Electronic address:

We solve high-dimensional steady-state Fokker-Planck equations on the whole space by applying tensor neural networks. The tensor networks are a linear combination of tensor products of one-dimensional feedforward networks or a linear combination of several selected radial basis functions. The use of tensor feedforward networks allows us to efficiently exploit auto-differentiation (in physical variables) in major Python packages while using radial basis functions can fully avoid auto-differentiation, which is rather expensive in high dimensions.

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Determining the optimal antibiotic duration for skin and soft tissue infections.

Curr Opin Infect Dis

January 2025

Department of Medicine, Clínica Rotger Quironsalud, Palma de Mallorca, Spain.

Purpose Of Review: Optimal duration of therapy in SSTIs - a heterogeneous group of infections - remains unknown. The advances in knowledge of antibiotic duration of treatment in selected SSTIs that can impact clinical practice and published in the last 18 months are reviewed.

Recent Findings: Recent evidence indicates that few patients receive guideline concordant empiric antibiotics and appropriate duration in the United States, although this likely can be extrapolated to other countries.

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The study focused on the coverage of Internally Displaced Persons (IDPs) in two selected newspapers. It aims to understand the extent and nature of the coverage of IDPs in these newspapers, taking into consideration the various reasons for displacement, such as conflicts and disasters, religious or political persecution, and economic necessity. Through an analysis of the selected newspapers, the study aims to shed light on the portrayal of IDPs, providing a comprehensive understanding of the issue and potential areas for improvement in media coverage.

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Background: The nomogram is a powerful and robust tool in disease risk prediction that summarizes complex variables into a visual model that is interpretable with a quantified risk probability. In the current study, a nomogram was developed to predict the occurrence of coronary artery lesions (CALs) among patients with Kawasaki disease (KD). This is especially valuable in the early identification of the risk of CALs, which will lead to proper diagnosis and treatment to reduce their associated complications.

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