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Exposure to Airborne Particulate Matter and Undernutrition in Young Rats: An In-Depth Histopathological and Biochemical Study on Lung and Excretory Organs.
Food Chem Toxicol
January 2025
Laboratorio de Bio-Toxicología Ambiental, Instituto de Tecnologías Emergentes y Ciencias Aplicadas. Escuela de Ciencia y Tecnología, Universidad Nacional de San Martín - CONICET. San Martín, Buenos Aires, Argentina; Cátedra de Anatomía Patológica. Facultad de Odontología, Universidad de Buenos Aires. Buenos Aires, Argentina.
Environmental stressors, such as air particulate matter (PM) and nutrient deficiencies, can significantly impact crucial organs involved in detoxifying xenobiotics, including lungs, liver, and kidneys, especially in vulnerable populations like children. This study investigated the effect of 4-week exposure to Residual Oil Fly Ash (ROFA) on these organs in young rats under growth-restricted nutrition (NGR). We assessed histological, histomorphometric and biochemical parameters.
View Article and Find Full Text PDFIn vitro culture and confocal microscopy study of Maritrema gratiosum Nicoll, 1907 (Digenea): From metacercaria to ovigerous adult.
Parasitol Res
January 2025
Institute of Aquaculture, University of Stirling, 5F.-2, No. 196, Sec. 2, Xinglong Rd., Wenshan Dist., Taipei City, 116096, Taiwan (R.O.C.).
This study set out to characterise the in vitro development, including musculature, of the microphallid parasite of the barnacle Semibalanus balanoides (Linnaeus, 1767), Maritrema gratiosum Nicoll, 1907 collected in Scotland. An in vitro culture model was developed to obtain ovigerous adults of M. gratiosum and their morphology was observed.
View Article and Find Full Text PDFCRRT Is More Than Just Continuous Renal Replacement Therapy.
Pharmaceuticals (Basel)
November 2024
Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
The physiology of the kidney has long been understood, and its mechanisms are well described. The pathology of renal failure is also a deeply researched area. It seems logical, therefore, to create devices that can replace the lost normal function of the kidney.
View Article and Find Full Text PDFEffects of Oregano Essential Oil and/or Yeast Cultures on the Rumen Microbiota of Crossbred Simmental Calves.
Animals (Basel)
December 2024
College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
This study hypothesized that combining oregano essential oil () and yeast cultures (s) would modulate rumen microbiota to promote gastrointestinal homeostasis and function. Twenty-four newborn, healthy, disease-free, crossbred Simmental male calves (birth weight ≥ 35 kg) were assigned to one of four treatments based on birth data. Treatments were as follows: (1) Control (), calves fed calf starter without additives; (2) , calves fed calf starter containing 60 mg/kg body weight () of OEO per day; (3) s, calves fed calf starter containing 45 mg/kg BW of YC per day; and (4) , calves fed calf starter with OEO (60 mg/kg, BW) and YC (45 mg/kg, BW) combination.
View Article and Find Full Text PDFTranscriptional responses to macrocyclic lactone exposure in larvae using RNA-seq.
bioRxiv
December 2024
Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS.
, the causative agent of zoonotic toxocariasis in humans, is a parasitic roundworm of canids with a complex lifecycle. While macrocyclic lactones (MLs) are successful at treating adult infections when used at FDA-approved doses in dogs, they fail to kill somatic third-stage larvae. In this study, we profiled the transcriptome of third-stage larvae derived from larvated eggs and treated with 10 μM of the MLs - ivermectin and moxidectin with Illumina sequencing.
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