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Article Synopsis
  • Wilms' tumor (WT) is primarily a childhood kidney cancer but can appear in adults, leading to diagnostic challenges and poor outcomes due to nonspecific symptoms and imaging.
  • A 45-year-old female with a history of hemodialysis was diagnosed with a right kidney tumor that had spread to the lung, identified using ultrasound and contrast-enhanced imaging techniques which highlighted its irregular characteristics.
  • This case emphasizes the significant role of ultrasound, especially contrast-enhanced ultrasound, in diagnosing adult WT, suggesting its potential to improve understanding and outcomes in similar cases.
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Interventions for preventing diarrhoea-associated haemolytic uraemic syndrome.

Cochrane Database Syst Rev

July 2021

Division of Pediatric Infectious Diseases, Department of Pediatrics, University at Buffalo, State University of New York, Buffalo, NY, USA.

Background: Haemolytic uraemic syndrome (HUS) is a common cause of acquired kidney failure in children and rarely in adults. The most important risk factor for development of HUS is a gastrointestinal infection by Shiga toxin-producing Escherichia coli (STEC). This review addressed the interventions aimed at secondary prevention of HUS in patients with diarrhoea who were infected with a bacteria that increase the risk of HUS.

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Background: Atypical haemolytic uraemic syndrome (aHUS) is a rare disorder characterised by thrombocytopenia, microangiopathic haemolytic anaemia, and acute kidney injury. The condition is primarily caused by inherited or acquired dysregulation of complement regulatory proteins with ~40% of those affected aged < 18 years. Historically, kidney failure and death were common outcomes, however, improved understanding of the condition has led to discovery of novel therapies.

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The rise and potential fall of pancreas transplantation.

Br Med Bull

December 2017

Oxford Transplant Centre, Nuffield Department of Surgical Science, University of Oxford, Churchill Hospital, Old Road, Oxford, OX3 7LE, UK.

Background: The aim of this review is to bring pancreatic transplantation out of the specialist realm, informing practitioners about this important procedure, so that they feel better equipped to refer suitable patients for transplantation and manage, counsel and support when encountering them within their own speciality.

Sources Of Data: Narrative review conducted in May 2017. OVID interface searching EMBASE and MEDLINE databases, using Timeframe: Inception to June 1, 2017.

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