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Associations of Short-Term Ozone Exposure With Hypoxia and Arterial Stiffness.

J Am Coll Cardiol

January 2025

SKL-ESPC & SEPKL-AERM, College of Environmental Sciences and Engineering, Center for Environment and Health, Peking University, Beijing, China; Research Station of Alpine Ecology Environment and Health at Tibet University, Lhasa, Tibet Autonomous Region, China. Electronic address:

Background: Epidemiological studies reported associations between ozone (O) exposure and cardiovascular diseases, yet the biological mechanisms remain underexplored. Hypoxia is a shared pathogenesis of O-associated diseases; therefore, we hypothesized that O exposure may induce changes in hypoxia-related markers, leading to adverse cardiovascular effects.

Objectives: This study aimed to investigate associations of short-term O exposure with hypoxic biomarkers and arterial stiffness.

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Cardiovascular diseases are a leading cause of death, and psychosocial stress is considered a contributing factor to these issues. With the rising number of heart surgeries, proper rehabilitation post-surgery is essential. Previous studies have demonstrated the positive impact of yoga and transcendental meditation on the cardiovascular system.

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"And that main artery's name is life": Ecosocial injury and resurgent care in Deanuleahki, Sápmi.

Med Anthropol Q

December 2024

Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.

Based on 28 months of ethnographic research in Deanuleahki-a river valley in Sápmi, the transborder Indigenous Sámi homeland-this article traces my interlocutors' striving to reclaim and repair ecological and kin relations through the everyday praxis of care. I trace this striving through the unmaking and remaking of local relations of care amidst encroachment by post-Second World War Nordic welfare states and regimes of environmental stewardship. I propose a dual conceptualization of ecosocial injury and resurgent care to account for, on the one hand, care's alienation from its social and ecological contexts; and, on the other, the intimate everyday labor of revivifying relations of kinship and belonging, and conditions of material livability, within local ecologies.

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Article Synopsis
  • Myo-inositol may help protect blood vessels from damage caused by environmental stressors, as shown in experiments with rat aortic rings and human plasma.
  • The study found that higher concentrations of myo-inositol (1-100 mg/L) reduced vascular contractions and promoted relaxation, while lower doses (≤ 0.1 mg/L) showed no effects.
  • Chemical analysis revealed that myo-inositol did not significantly affect physiological processes in the aortic rings during the incubation, but it did protect against oxidative stress and improve blood coagulation metrics.
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Background: This study investigated the relationship between lipid-associated loci identified through genome-wide association studies (GWAS) and the risk of peripheral artery disease (PAD), its severity, as well as clinical and laboratory features.

Research Design And Methods: A study included 1263 unrelated Russian subjects, consisting of 620 patients diagnosed with PAD and 643 healthy controls. Thirteen single nucleotide polymorphisms (SNP) were genotyped using the MassArray-4 system.

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