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CEACAM5 exacerbates asthma by inducing ferroptosis and autophagy in airway epithelial cells through the JAK/STAT6-dependent pathway.
Redox Rep
December 2025
Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.
Objectives: Asthma, a prevalent chronic disease, poses significant health threats and burdens healthcare systems. This study focused on the role of bronchial epithelial cells in asthma pathophysiology.
Methods: Bioinformatics was used to identify key asthmarelated genes.
Impact of Birth Order on Paediatric Allergic Diseases: A National Birth Cohort in Japan.
Clin Exp Allergy
January 2025
Department of Pediatrics, Okayama University, Graduate School of Medicine, Density and Pharmaceutical Science, Okayama, Japan.
Objective: To assess the Knowledge, Attitudes and Practices (KAP) among healthcare professionals in managing patients with coexisting hypertension and bronchial asthma.
Design: A cross-sectional survey. The reporting of this study followed the Strengthening the Reporting of Observational Studies in Epidemiology checklist.
Burdens of Tracheal, Bronchus, and Lung Cancer From 1990 to 2021 in China Compared to the Global Projection of 2036: Findings From the 2021 Global Burden of Disease Study.
Thorac Cancer
January 2025
Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Tracheal, bronchial, and lung cancers (TBL cancers) pose a significant global health challenge, with rising incidence and mortality rates, particularly in China. Studies from the Global Burden of Disease (GBD), 2021, can guide screening and prevention strategies for TBL cancer. This study aims to provide a comprehensive analysis of the burden of TBL cancers in China compared to global data.
View Article and Find Full Text PDFFactors influencing health-related quality of life in children with asthma: insights from Addis Ababa public hospitals.
Front Public Health
January 2025
College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.
Background: Bronchial asthma is a global health problem in particular a respiratory condition characterized by broncho spasms that negatively affect the quality of life (QOL) of children. However, there is a paucity of data regarding the health-related quality of life of asthma in children in Ethiopia, and the study area.
Objective: The objective of this study was to assess the health-related quality of life among asthmatic children aged 7-17 in selected hospitals in Addis Ababa, Ethiopia.
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