Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1748-1716.1974.tb05766.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Determination of metal ion transport rate of human ZIP4 using stable zinc isotopes.
J Biol Chem
September 2024
Department of Chemistry, Michigan State University, East Lansing, Michigan, USA; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA. Electronic address:
The essential microelement zinc is absorbed in the small intestine mainly by the zinc transporter ZIP4, a representative member of the Zrt/Irt-like protein (ZIP) family. ZIP4 is reportedly upregulated in many cancers, making it a promising oncology drug target. To date, there have been no reports on the turnover number of ZIP4, which is a crucial missing piece of information needed to better understand the transport mechanism.
View Article and Find Full Text PDFA flow equilibrium of zinc in cells of .
J Bacteriol
May 2024
Martin-Luther-University Halle-Wittenberg, Institute for Biology/Microbiology, Halle (Saale), Germany.
Unlabelled: The hypothesis was tested that a kinetical flow equilibrium of uptake and efflux reactions is responsible for balancing the cellular zinc content. The experiments were done with the metal-resistant bacterium . In pulse-chase experiments, the cells were loaded with radioactive Zn and chased with the 100-fold concentration of non-radioactive zinc chloride.
View Article and Find Full Text PDFSupplementation of zinc mitigates the altered uptake and turnover of 65Zn in liver and whole body of diabetic rats.
Biometals
December 2011
Department of Biotechnology, GGDSD College, Sector-32, Chandigarh, India.
Diabetes is a life threatening disease and its onset is linked with both environmental and genetic factors. Zinc metabolism gets altered during diabetes and results in many complications. The present study was designed to elucidate the effects of zinc supplementation on the biokinetics of (65)Zn in whole body, liver and its biodistribution in diabetic rats.
View Article and Find Full Text PDFDevelopment of a compartmental model of zinc kinetics in mice.
J Nutr
November 2008
Metabolic Modeling Services, 7201 Blenheim, New Zealand.
To investigate zinc (Zn) kinetics in mice, tracer ((65)Zn) was administered orally to 9-wk-old female mice in the fed state and tracer and Zn concentration were measured in 21 tissues over the following 8 d. Data were analyzed by compartmental modeling using WinSAAM. A published model for Zn kinetics in rats was modified to fit the data from mice and to calculate transfer rates and pool sizes of Zn.
View Article and Find Full Text PDFInfluence of zinc on the status of hepatic trace elements and biokinetics of 65Zn in ethanol treated rats.
Indian J Exp Biol
March 2005
Department of Biophysics, Panjab University, Chandigarh 160 014, India.
Whole body counting studies of 65Zn indicated that the Tb1 (the faster component) was significantly decreased while the slower component (Tb2) was increased significantly following ethanol treatment. Interestingly, following zinc treatment to ethanol treated rats, slower component (Tb2) of 65Zn came back to within normal limits while the faster component (Tb1) got significantly elevated in comparison to ethanol treatment. Percent uptake values of 65Zn were found to be increased in liver, intestine, muscle, brain and kidney, and decreased in bone under alcoholic conditions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!